Titel: | CREB Target Gene Database |
Identifier: | http://natural.salk.edu/CREB/ |
Autor: | Montminy, Marc |
Veröffentlicht durch: |
Salk Institute |
Zusammenfassung: |
The cyclic AMP response element (CRE)-binding protein (CREB) family of activators (CREB1, CREM, ATF1) functions in diverse physiological processes, including the control of cellular metabolism, growth-factor-dependent cell survival, and developement an plasticity of neurons. A diverse range of signals, including cAMP, calcium, stress and mitogenic stimuli, can activate CREB and promote target gene expression. This database is dedicated to catogerize CREB target genes in a comprehensive and easy-to-search way. We have used a multi-layered approach to predict, validate and chracterize CREB target genes. For each gene, we try to provide the following information: 1. CREB binding sites on the promoters, 2. Promoter occupancy by CREB, 3. Gene activation by cAMP in tissues. The data are for humans, rats, and mice. [Information of the supplier, modified] Die Datenbank enthält Fakten: genetische Informationen (Interaktion mit Aktivatorprotein). Sie ist kostenfrei verfügbar. |
Thema: |
Biochemische Genetik der Tiere (572.81)
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Zielgruppe: | Fortgeschrittene; Experten |
Sprache: | Englisch |
Format: | Website; Datenbank |
Ressourcentyp: | Fakten-Datenbanken |
Zugang: | frei |
Letzte Änderung des Metadatensatzes: | 10.09.2015 |
Metadatenlieferant: | |
URL dieses vifabio-Datensatzes: | http://www.vifabio.de/iqfBio/detail/1495 |
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