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Classification of Protein Domains
Classification of Protein Domains
| Titel: | Classification of Protein Domains |
| Titel Kurzform: | CATH |
| Identifier: | http://www.cathdb.info/cgi-bin/search.pl?search_text= |
| Autor: | Orengo, C.A.; et al. |
| Veröffentlicht durch: |
University College |
| Urheberrecht: | http://www.biochem.ucl.ac.uk/bsm/cath/ |
| Zusammenfassung: |
CATH is a hierarchical classification of protein domain structures, which clusters proteins at four major levels, Class(C), Architecture(A), Topology(T) and Homologous superfamily (H).Class, derived from secondary structure content, is assigned for more than 90% of protein structures automatically. Architecture, which describes the gross orientation of secondary structures, independent of connectivities, is currently assigned manually. The topology level clusters structures into fold groups according to their topological connections and numbers of secondary structures. The homologous superfamilies cluster proteins with highly similar structures and functions. The assignments of structures to fold groups and homologous superfamilies are made by sequence and structure comparisons. The boundaries and assignments for each protein domain are determined using a combination of automated and manual procedures. These include computational techniques, empirical and statistical evidence, literature review and expert analysis. [Information of the supplier] Sequenzmodelierung |
| Thema: |
Proteine (572.6); DNS (Desoxyribonukleinsäure) (572.86) » finde ähnliche Quellen! |
| Zielgruppe: | Experten |
| Sprache: | Englisch |
| Format: | Website |
| Ressourcentyp: | Fakten-Datenbanken |
| Zugang: | frei |
| Letzte Änderung des Metadatensatzes: | 11.05.2012 |
| Metadatenlieferant: |
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| URL dieses vifabio-Datensatzes: | http://www.vifabio.de/iqfBio/detail/1067 |
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