Antimicrobial peptides, also referred to as host defense peptides or "alarmins", have been identified in nearly all life forms, ranging from bacteria, fungi, plants, insects, amphibians, to mammals, including humans. As the key component of the innate immunity, these ancient peptides effectively eliminate invanding microbes such as bacteria, viruses, fungi, and parasites. It is commonly believed that cationic antimicrobial peptides exert their effects via attacking anionic bacterial membranes. Currently, there is high interest worldwide in this topic with a goal of understanding the mechanism of action and developing natural antimicrobial peptides into a new generation of antibiotics. To promote the research, education, and information exchange in the field, we have created this antimicrobial peptide database and data analysis system. The data stored in APD2 were gleaned from the Protein Data Bank (PDB), Swiss-Prot Protein Knowledgebase and PubMed National Library of Medicine. The peptides in this database are in the mature and active form and primarily from natural sources ranging from bacteria, plants, insects, to animals. ... [Information of the supplier]
This dataset contains 99 genes and comes from Catalina Betancur's review published in Brain Research in 2011 (Betancur, 2011). Different genetic and genomic disorders in which ASDs have been described as one of the possible manifestations were collected. Genes, CNVs and linkage regions associated with autism were searched from literature and curated. Six categories of literatures were included in our collection: genome-wide association studies, expression profiling, genome-wide CNV studies, linkage analysis, low-scale genetic association studies and other low-scale gene studies. Representative meta-data about key clinical and demographic characteristics was collected. ... [Information of the supplier]
The Pest Information Wiki has a literature database where each publication page contains information on which pests, diseases, or weeds the publication deals with. Related information like which research topic, host plants or field location (country or part of a country) the article has been covering can also be included in a publication page. These data can then be retrieved on other pages. For example, a page on a pest can then display lists of literature which are relevant to this pest, like lists sorted by research topics (e.g. Bibliography:Leptinotarsa decemlineata) or lists of distribution records or host plant records (e.g. see the top left in the page Leptinotarsa decemlineata). ... [Information of the supplier]
The CEBS database houses data of interest to environmental health scientists. CEBS is a public resource, and has received depositions of data from academic, industrial and governmental laboratories. CEBS is designed to display data in the context of biology and study design, and to permit data integration across studies for novel meta analysis. ... [Information of the supplier]
The purpose is the creation of a comprehensive computer supported decision/help system for pharmacotherapy and clinical toxicology. At present, CliniPharm/CliniTox has the following components: 1) an animal medicine compendium for Switzerland; 2) specialist information about therapeutic substances; 3) CliniTox, a computer supported decision/help system for the management of cases of poisoning in animals (incl. a poisonous plant database that contains, besides relevant veterinary medical data, botanical information as well as pictures of the individual plants. Because of the multilingual nature of Switzerland the plants can be searched for not only by their scientific names, but also by their common German, French, Italian, and English names.) ... [Information of the supplier, translated and modified]
The Cornell Plant Pathology Herbarium (CUP) is a large research collection of preserved fungi and other organisms that cause plant diseases. CUP is the fourth or fifth largest mycological herbarium in North America. We hold about 400,000 fungus and plant disease specimens, including over 7000 type specimens, each the first of its kind to be described and named. The CUP Photograph Collection includes about 60,000 historical scientific photographs of mushrooms, agricultural practices, plant diseases, and portraits. ... [Information of the supplier]
Database of Bacterial ExoToxins for Human (DBETH) is a database of sequences, structures, interaction networks and analytical results for 229 exotoxins, from 26 different human pathogenic bacterial genus. All toxins are classified into 24 different Toxin classes. The aim of DBETH is to provide a comprehensive database for human pathogenic bacterial exotoxins. DBETH also provides a platform to its users to identify potential exotoxin like sequences through Homology based as well as Non-homology based methods. In homology based approach the users can identify potential exotoxin like sequences either running BLASTp against the toxin sequences or by running HMMER against toxin domains identified by DBETH from human pathogenic bacterial exotoxins. In Non-homology based part DBETH uses a machine learning approach to identify potential exotoxins (Toxin Prediction by Support Vector Machine based approach). ... [Information of the supplier]
The potential of a pesticide or biocide to cause adverse effects in the developing embryo or fetus is an important consideration in any health risk assessment for humans and wildlife. Such information is usually derived from experimental studies in which pregnant laboratory animals are exposed to various concentrations of compounds during critical stages of fetal development. The terms and diagnostic criteria used to describe fetal anomalies need to be consistent from one laboratory to another. Consequently, the DevTox Project has three main objectives: To harmonize the nomenclature used to describe developmental anomalies in laboratory animals, to assist in the visual recognition of developmental anomalies with the aid of photographs, and to provide a historical control database of developmental effects in laboratory animals. ... [Information of the supplier]
The Ecological Database of the World's Insect Pathogens (EDWIP) offers information on fungi, viruses, protozoa, mollicutes, nematodes, and bacteria¹ that are infectious in insects, mites, and related arthropods. Data in EDWIP include associations (or lack thereof) between pathogenic organisms and insect, mite, and other arthropod hosts. EDWIP also includes information on where associations have been observed, stages and tissues of hosts infected, and habitats and host ranges of the arthropod hosts. Association and nonassociation data in EDWIP are supported by bibliographic citations. All areas of the database are searchable. (....) ¹Because of the tremendous volume of information available on the bacterial pathogen Bacillus thuringiensis, we have excluded this species from EDWIP. For informaton on Bt, see the Canadian Forest Service's Bt Toxin Specificity Database. ... [Information of the supplier]
The ECOTOXicology database (ECOTOX) is a source for locating single chemical toxicity data for aquatic life, terrestrial plants and wildlife. ECOTOX was created and is maintained by the U.S.EPA, Office of Research and Development (ORD) , and the National Health and Environmental Effects Research Laboratory's (NHEERL's) Mid-Continent Ecology Division (MED). ECOTOX integrates three previously independent databases - AQUIRE, PHYTOTOX, and TERRETOX - into a unique system which includes toxicity data derived predominately from the peer-reviewed literature, for aquatic life, terrestrial plants, and terrestrial wildlife, respectively. ... [Information of the supplier]