The Blood Group Antigen Gene Mutation Database (BGMUT) was set up under the aegis of the Human Genome Variation Society (HGVS) in 1999. It documents variations in genes that encode antigens for human blood groups. It thus is a locus-specific mutation database (LSDB) that covers multiple genes. The database was compiled and has been curated by Olga O. Blumenfeld, PhD, Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, and Santosh K. Patnaik, MD, PhD, Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo NY. In 2006, this website moved to the NCBI to become part of dbRBC where it has been under the direction and additional curatorship of Wolfgang Helmberg, MD, Department of Serology and Transfusion Medicine, Medical University of Graz, Austria. Many who are experts in the study of blood group systems have contributed to the development of this database by providing, among other things, information on the systems and the alleles. In addition to documenting genetic variations, this site also provides information on the blood group systems, the genes that encode them, the serological phenotypes, etc. Blood group systems for which genes or genetic variations have yet to be identified are also documented. For some systems, information on non-human orthologous genes is also made available. ... [Information of the supplier]
The Thirteenth International Conference on Endothelin will be held at Tokyo Campus of Tsukuba University in Tokyo, Japan, September 8-11, 2013. In the tradition of the meeting rotating between the continents the conference this time will be again held in Asia and will provide a forum for cutting-edge science in endothelin and endothelin receptor antagonism research and it will represent the 25th anniversary of the International Conferences on Endothelin since the first conference was held in in 1988 shortly after the discovery of endothelin at the University of Tsukuba. As an international biomedical research conference, ET conferences have been previously attended by several hundred scientists and clinicians from around the world. Continuing the meeting's tradition, novel findings on the role of endothelin and its receptors in molecular biology, development, pharmacology, general physiology, and pathophysiology will be presented. Most recent results from clinical trials of endothelin antagonism in patients will also be presented. ... [Information of the supplier]
The American Physiological Society’s (APS) Seventeenth International Conference on Endothelin (ET-17) will be held live virtually October 4–7, 2021. This biennial event is the premier forum for scientists to meet and discuss recent research developments in endothelin (ET)—an amino acid chain secreted by vascular endothelial cells—as well as clinical applications of blocking the ET system and the use of ET as a biomarker for disease. ... [Information of the supplier]
Based on the mapping of the human genome and the development of information databases, a broad description of genes transcribed in blood cells is now known. Hembase was developed to provide worldwide access to those genetic-based studies performed by scientists in the Molecular Biology and Genetics Section, Molecular Medicine Branch, Division of Intramural Research, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This project represents the shared goal of several individuals and groups (credits) interested in disseminating genomic information on the World Wide Web. ... [Information of the supplier]
Linus Pauling began his professional life studying atoms, and ended it best known for his thoughts on medicine. Linking these two fields was a central body of work on the nature of human blood. During the most productive thirty years of his life, between the mid-1930s and mid-1960s, Pauling's research in this area not only advanced our understanding of how the blood works at the molecular level, but branched and blossomed into vital discoveries about immunology, sickle-cell anemia, genetics, evolution, and human health. Incorporating more than 300 scanned documents, photographs, audio clips and video excerpts, this web resource includes images of a number of very important and extremely rare items, most of which are held within The Valley Library's Ava Helen and Linus Pauling Papers, many of which have not been previously displayed. The site is designed to serve as both an introduction to an important body of work and as a reference tool for students, teachers, physicians, scientists, and members of the general public interested in the history of modern medicine. ... [Information of the supplier]
"Neuroguide.com" is a searchable and browsable index of neuroscience resources available on the Internet: Neurobiology, neurology, neurosurgery, psychiatry, psychology, cognitive science sites and information on human neurological diseases. [Information of the supplier]
BioMed Central is a publisher of more than 150 peer-reviewed open access journals. The research articles in all journals published by BioMed Central are 'Open Access'. They are immediately and permanently available online without charge. A number of journals require an institutional or a personal subscription to view other content, such as reviews or paper reports. Free trial subscriptions to these journals are available. ... [Information of the supplier]
The p53 tumor suppressor gene was initially identified as being essential for the DNA damage checkpoint, but it was subsequently found to have a broader function after cellular stress, such as oncogene activation or hypoxia. The p53 protein functions as a tetrameric transcription factor found at very low levels in normal unstressed cells. After stress, different pathways lead to post-translational modification of the protein and its stabilization. p53 database contains 16,000+ entries corresponding to TP53 mutations found in tumors, normal skin, and noncancerous diseases such as rheumatoid arthritis. The database also includes germline mutations found in Li-Fraumeni syndrome (LFS) and LFS-like syndrome. ... [Information of the supplier, modified]
The HIV databases contain data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, and vaccine trials. The website also gives access to a large number of tools that can be used to analyze these data. This project is funded by the Division of AIDS of the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH). ... [Information of the supplier]
The tasks of the Robert Koch Institute include the monitoring of emerging diseases and risk factors in the general population as well as the provision of scientific research. This allows appropriate measures to protect the general public health to be taken in a rapid and effective way. These tasks make the RKI the central institution and the coordination centre for the Federal Ministry for Health for applied and basic research in the areas of infectious diseases, including infection epidemiology and epidemiology of non-transmissible diseases. On this basis, the RKI is in the position to suggest measures for intervention and prevention, to fill gaps in the knowledge and ensure the quality of health screening and care. The RKI takes part in the preparation of guidelines, recommendations and expert opinions for the federal government, the parliament, the scientific sector and other health-related political issues. ... [Information of the supplier]
