Uptake of foreign mobile genetic elements is often detrimental and can result in cell death. For protection against invasion, prokaryotes have developed several defence mechanisms, which take effect at all stages of infection. The most recent discovered defence system is the prokaryotic immune system, termed CRISPR/Cas. This defence system directly degrades invading genetic material and is present in almost all archaea and many bacteria. Current data indicate a large variety in their mechanistic molecular approaches. This meeting is the 3rd European CRISPR Meeting after the previous meetings in Wageningen 2010 (organised by John van der Oost, Stan Brouns, Edze Westra, Philippe Horvath) and in St. Andrews 2013 (organised by Malcolm White, John van der Oost, Emanuelle Charpentier). The meeting is sponsored by the DFG Research Group "Unravelling the prokaryotic immune system" (FOR1680). Leading international experts on CRISPR/Cas will give lectures, additional oral presentations will be selected from submitted abstracts. Poster presentations will give scientists the opportunity to discuss their current work. Sessions will cover the following topics: evolution of the CRISPR/Cas system, CRISPR/Cas systems I-III, virus-host interactions and applications and Genome Editing and CRISPRi. ... [Information of the supplier]
