The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body. It is intended to be used for applications in metabolomics, clinical chemistry, biomarker discovery and general education. The database is designed to contain or link three kinds of data: 1) chemical data, 2) clinical data, and 3) molecular biology/biochemistry data. The database currently contains nearly 2500 metabolite entries including both water-soluble and lipid soluble metabolites as well as metabolites that would be regarded as either abundant (> 1 uM) or relatively rare (< 1 nM). ... [Information of the supplier]
The word "aging" encompasses a range of physiological changes in humans, human tissues, and constituent cells. Alterations in metabolism, whether at the level of small molecules, protein homeostasis, signaling patterns, or intertissue communication, underpin many of the processes that ultimately decline or shift during aging. The recent wealth of information on how perturbation of metabolic factors can accelerate or impair aging processes makes this an exciting time to convene and consider the new biology being uncovered, its potential impact on human health, and the implications for the coming age of precision medicine. This meeting brings together scientists who have interests in aging and metabolism to explore the growing intersection between these fields and to discuss key questions in this area for human health and disease. Leaders in the field will share results from cellular research, investigations in model organisms, and studies with translational impact rooted in mammalian systems. ... [Editorial staff vifabio]
The field of immunometabolism has thrived over the last decade, revealing not only the major roles played by immune cells in metabolic homeostasis but also the impact of metabolic pathways on immune cell function. As new discoveries continue to reveal the intricate links between immunology and metabolism, a key question arises: will our accumulated knowledge on immunometabolic deregulations translate into novel therapies for human diseases? During this Cell Symposium, you will hear about the latest advances in immunometabolism from physician-scientists, basic researchers and industry leaders. We will discuss how local and systemic metabolism are integrated at the cellular level to regulate immune cell function and we will focus on how novel insights into immunometabolism can be harnessed to advance and/or bolster therapeutic interventions in metabolic diseases, inflammation, autoimmunity, and cancer. ... [Information of the supplier]
Reliable information on marine bioluminescence is widely scattered in the literature and in unpublished data. While this is merely an inconvenience to the relatively small core of investigators actively working in the discipline, there is a much larger group of life scientists, oceanographers and applied marine scientists who frequently come upon problems involving bioluminescence and who might have little awareness of the availability and reliability of information on the subject. ... [Information of the supplier]
Sequencing of the human genome has opened the way and provided the impetus for building a comprehensive picture of a mammalian cell. Significant efforts are underway in the fields of genomics and proteomics to identify all genes and proteins in a given organism. The goal is a complete map of the genes, gene products and their interaction networks in a functioning cell. The next step in establishing a comprehensive picture of a cell will be to tie the cell's metabolome into the rapidly developing genomic and proteomic maps. A cell's metabolome, however, is such an enormous and complex entity that characterizing it can only be approached in sections. This consortium is now proposing to focus on the lipid section of the metabolome by developing an integrated metabolomic system capable of characterizing the global changes in lipid metabolites ("lipidomics"). Our consortium has developed a Lipid Metabolites and Pathways Strategy, termed LIPID MAPS, that applies a global integrated approach to the study of lipidomics. ... [Information of the supplier]
This page gives access to the digitized version of the Roche Applied Science "Biochemical Pathways" wall chart. The Biochemical Pathway posters are available as paper copy from Roche. Please enter one or more keyword(s) or partial word(s). For example, you may type Oxoacyl. You will then be given a list of all matching entries of the "Biochemical Pathways" wall chart. This list contains links to the ENZYME Database and, for each entry, links to all maps of "Biochemical Pathways" in which this entry appears. You can also access the individual images by clicking in a reduced image of an entire section of the wall chart (thumbnail view for "Metabolic Pathways" and "Cellular and Molecular Processes"). ... [Information of the supplier, modified]
This site will present relevant information on photosynthesis-related web sites grouped into several categories: 1) large group sites, 2) comprehensive overview sites, 3) specific subject sites, 4) individual researcher sites, 5) kindergarten (K)-12 educational sites, 6) books and journals, and, 7) other useful sites. ... [Information of the supplier, modified]
John Illingworth von der Faculty of Biological Science an der Universität Leeds, Großbritannien, stellt auf dieser Seite Lerneinheiten für Studenten zu verschiedenen Themen aus dem Bereich Biochemie/Stoffwechsel und zu Methoden zur Verfügung. [Redaktion vifabio]
Die Homepage von PD Dr. Dieter Weiß, tätig am Institut für Organische Chemie und Makromolekulare Chemie der Universität Jena, informiert über die Themen Lumineszenz, Chemielumineszenz und Bioluminseszenz. Es werden sowohl Begriffserklärungen für die verschiedenen Lumineszenzarten gegeben, als auch der Versuch unternommen, die chemischen Grundlagen zu erläutern. ... [Redaktion vifabio]
hiPathDB provides two different types of integration. The pathway-level integration is a simple collection of individual pathways as described in the original database. We devised a gene-centric pathway model that could reflect different properties of four databases. The entity-level integration creates a super pathway that merged all pathways by unifying redundant components. Even though the detailed molecular information such as complex formation or modification can be lost in some cases, the merged superpathway provides a unified view of current knowledge on human pathways, which is critical to understand relationships among different pathways. Another strong merit of hiPathDB is the built-in pathway visualization module to support explorative study of complex networks in an interactive fashion. The force-directed layout algorithm is optimized for almost automatic visualization of pathways. ... [Information of the supplier]
