GBOL - German Barcode of Life: → Inventarisierung und genetische Charakterisierung der Tiere, Pflanzen und Pilze Deutschlands. Das GBOL-Projekt hat das Ziel die Artenvielfalt aller deutschen Tiere, Pilze und Pflanzen anhand ihres genetischen DNA-Barcodes (Fingerabdrucks) zu erfassen. Damit übernimmt Deutschland als Wissenschaftsnation eine führende Rolle in einem internationalen Konsortium aus Naturkundemuseen, Zoos, Herbarien, Forschungseinrichtungen und staatlichen Institutionen, die den Aufbau einer "DNA Barcode Bibliothek des Lebens" (pdf) zum Ziel haben. Bis heute sind weltweit ~1,5 Millionen DNA Barcodes von ~145.000 beschriebenen Arten in der BOLD Datenbank erfasst (Stand: Dez. 2011). GBOL ist ein deutschlandweites Netzwerk aus verschiedenen Naturkundemuseen und anderen Biodiversitätsforschungsinstituten. Die GBOL Partner stellen ihre professionelle taxonomische Expertise und ihre bereits existierende Infrastruktur (Sammlungen/Biobanken, Datenbanken, Bioinformatik-Plattformen und Labore) zur Verfügung, um umfassend und flächendeckend die Tier- und Pflanzenarten Deutschlands zu sammeln, zu katalogisieren, wissenschaftlich zu beschreiben, zu sequenzieren und in die globale Referenz-Barcode Datenbank „BOLD“ einzuspeisen. Die morphologische Artidentifikation wird zunächst durch spezialisierte Experten (Taxonomen) erfolgen, die ihr Wissen über die Morphologie, Ökologie, Reproduktionsmodus und Lebenszyklus bestimmter Taxa einbringen. Mit modernsten DNA Sequenziermethoden wird in einem zweiten Schritt der DNA Barcode entschlüsselt. Der Artensteckbrief wird mit dem DNA Barcode verknüpft und in einer öffentlich zugänglichen DNA Barcode Referenz-Datenbank verfügbar gemacht. Die professionellen GBOL Taxonomen sind bei dieser Aufgabe besonders auf die tatkräftige Unterstützung und Kooperation von ehrenamtlichen Taxon-Experten aus ganz Deutschland angewiesen. ... [Information des Anbieters]
This symposium focuses on the interface of ecology and evolutionary genetics, with special emphasis placed on the interaction between organisms as a basis for understanding ecological adaptation. New sequencing-based methods are bridging the gap between modern genetics and systems-level ecological studies. This is paralleled by dramatic improvements in imaging and remote sensing, with which one can capture both spatial and temporal components of dynamic interactions between individuals and their natural environment. ... [Information of the supplier]
SRS (sequence retrieval system) is one of the most powerful data browsing/retrieval tools available. SRS provides rapid, easy and user friendly access to the large volumes of diverse and heterogeneous Life Science data stored in more than 400 internal and public domain databases. It can be used to browse the various biological sequence and literature databases the EBI has available. ... [Information of the supplier]
BioMagResBank (BMRB) is the publicly-accessible depository for NMR results from peptides, proteins, and nucleic acids recognized by the International Society of Magnetic Resonance and by the IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy. In addition, BMRB provides reference information and maintains a collection of NMR pulse sequences and computer software for biomolecular NMR. Access to data in BMRB is free directly from its web site (URL http://www.bmrb.wisc.edu) and ftp site (ftp.bmrb.wisc.edu) and will remain so as public funding permits. The concept of a biomolecular NMR data bank was developed under a five-year research grant awarded to the University of Wisconsin-Madison from the National Library of Medicine, National Institutes of Health. ... [Information of the supplier]
The Bioinformatics Links Directory features curated links to molecular resources, tools and databases. All of the resources are free or available for a nominal fee. The links listed in this directory are selected on the basis of recommendations from bioinformatics experts in the field. We make every effort to list useful, well tested resources instead listing all tools. ... [Information of the supplier]
Many resources (e.g. Nature Reviews Genetics) offer a 10,000-foot view of the current trends in the field, reviews of various technologies, and guidelines on how to effectively design, analyze, and interpret experiments in human genetics and bioinformatics research. By comparison very few resources focus on the mundane, yet critical know-how for those on the ground actually doing the science (i.e. grad students, postdocs, analysts, and junior faculty). Getting Genetics Done aims to fill that gap by featuring software, code snippets, literature of interest, workflow philosophy, and anything else that can boost productivity and simplify getting things done in human genetics research. ... [Information of the supplier]
Individualised medicine based on patient genomes will have an enormous impact on healthcare. With breakthroughs in DNA sequencing technology, the number of sequenced genomes could reach >1 Million within 5–10 years. The simultaneous generation and integration of this associated molecular and clinical data will provide an unprecedentedly rich set of “big data” for basic research and translation. Integration of these data will provide new research opportunities, for example, through the identification of novel biomarkers or by enabling the identification of causal relationships in molecular biology through analysing complex datasets, but will also come with significant technical and bioethical challenges. This EMBL-Wellcome Genome Campus Conference on “Big Data in Biology & Health” will be held at EMBL Heidelberg, and will alternate between Heidelberg and Hinxton yearly to address the opportunities and challenges of “big data” analytics, advance basic research and explore translational opportunities. This timely interdisciplinary meeting aims to enable the European research community to participate in and help drive the future development of “big data” research, as well as raise further awareness for this new and relevant research direction in the life sciences. ... [Information of the supplier]