The building blocks of life – macromolecules, cells, tissues, and organs – act on each other via physical forces. This interplay of physical forces between the units of life gives rise to complex behaviour — enables motility, transport, growth, division, response to environmental cues, and allows the exertion of forces on the environment, bridging biological scales. The alteration of forces and mechanical properties is associated with inflammation, cancer, and ageing. This comprehensive symposium will study the interplay of the physical forces — the mechanics — between the fundamental building blocks of life, from molecules to organs. It will cover how these physical forces enable development and how they are altered in disease. We will cover the physical mechanisms of the major components of the animal cell and its environment, including cell membranes, cytoskeleton, the nucleus, and the extracellular matrix. It will focus on the role of mechanical forces in both development and disease, engaging clinicians, cell and developmental biologists, and physical and material scientists, from in silico to in vitro and to in vivo studies. We will include state-of-the-art technological applications that rely on the knowledge and use of mechanical forces for biotechnological and healthcare purposes. ... [Information des Anbieters]
This symposium, initiated in 2010, has taken place every second year since and brings together early-career and established researchers from all over the world who are interested in microtubule biology and its impact on human health and disease. The microtubule cytoskeleton is essential for a wide variety of cellular functions, such as chromosome segregation, directed vesicle and organelle transport, cell motility, and cell polarity. Impaired microtubule function can lead to human diseases including cancer and neurodegenerative disorders, where microtubules serve as important therapeutic targets. In recent years, interdisciplinary approaches embracing cell biology, genetics, molecular biology, biochemistry, biophysics, structural biology, and mathematical modelling have made a tremendous impact on microtubule research. The progressive diversification of the microtubule field creates the need for this strong meeting that unifies the community and brings together researchers from different disciplines interested in microtubule research. As per the now well-established format, the 2024 edition of the symposium will feature inspirational keynote and landmark lectures, a large number of short talk opportunities selected from the submitted abstracts, lively poster sessions, and activities for networking. ... [Information des Anbieters]
As in previous years, the 27th STS Meeting will be organized as a Joint Meeting of the Signal Transduction Society with signaling study groups of the German Societies for Immunology (DGfI) and Cell Biology (DGZ), the Society for Biochemistry and Molecular Biology (GBM), the German Society for Pharmacology (DGP), and the Collaborative Research Center "Structural Dynamics of GPCR Activation and Signaling" (SFB1423). If other organizations are interested in joining future STS Meetings, please contact the STS President Prof. Dr. Katharina Hieke-Kubatzky. ... [Information des Anbieters]
