PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes. Each entry in PHI-base is curated by domain experts and is supported by strong experimental evidence (gene disruption experiments, STM etc), as well as literature references in which the original experiments are described. Each gene in PHI-base is presented with its nucleotide and deduced amino acid sequence, as well as a detailed description of the predicted protein's function during the host infection process. To facilitate data interoperability, we have annotated genes using controlled vocabularies and links to external sources. ... [Information of the supplier]
HSDB is a toxicology data file on the National Library of Medicine's (NLM) Toxicology Data Network (TOXNET®). It focuses on the toxicology of potentially hazardous chemicals. It is enhanced with information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data are referenced and derived from a core set of books, government documents, technical reports and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review Panel (SRP), a committee of experts in the major subject areas within the data bank's scope. HSDB is organized into individual chemical records, and contains over 5000 such records. ... [Information of the supplier]
Antimicrobial peptides, also referred to as host defense peptides or "alarmins", have been identified in nearly all life forms, ranging from bacteria, fungi, plants, insects, amphibians, to mammals, including humans. As the key component of the innate immunity, these ancient peptides effectively eliminate invanding microbes such as bacteria, viruses, fungi, and parasites. It is commonly believed that cationic antimicrobial peptides exert their effects via attacking anionic bacterial membranes. Currently, there is high interest worldwide in this topic with a goal of understanding the mechanism of action and developing natural antimicrobial peptides into a new generation of antibiotics. To promote the research, education, and information exchange in the field, we have created this antimicrobial peptide database and data analysis system. The data stored in APD2 were gleaned from the Protein Data Bank (PDB), Swiss-Prot Protein Knowledgebase and PubMed National Library of Medicine. The peptides in this database are in the mature and active form and primarily from natural sources ranging from bacteria, plants, insects, to animals. ... [Information of the supplier]
VectorBase is a web-accessible data repository for information about invertebrate vectors of human pathogens. VectorBase annotates and maintains vector genomes providing an integrated resource for the research community. Currently, VectorBase contains genome information for two organisms: Anopheles gambiae, a vector for the Plasmodium protozoan agent causing malaria, and Aedes aegypti, a vector for the flaviviral agents causing Yellow fever and Dengue fever. (Lawson, D. et al., 2007: VectorBase: a home for invertebrate vectors of human pathogens. - Nucleic Acids Research 35: D503-D505; doi:10.1093/nar/gkl960.) ... [Information of the supplier]
The potential of a pesticide or biocide to cause adverse effects in the developing embryo or fetus is an important consideration in any health risk assessment for humans and wildlife. Such information is usually derived from experimental studies in which pregnant laboratory animals are exposed to various concentrations of compounds during critical stages of fetal development. The terms and diagnostic criteria used to describe fetal anomalies need to be consistent from one laboratory to another. Consequently, the DevTox Project has three main objectives: To harmonize the nomenclature used to describe developmental anomalies in laboratory animals, to assist in the visual recognition of developmental anomalies with the aid of photographs, and to provide a historical control database of developmental effects in laboratory animals. ... [Information of the supplier]
This is the Hyperlinked Human Histology (HHH) Home Page. This is being developed for students to use when they want to tie together the micro and the macro of immunology. For example, in immunology classes, students learn about the proteins involved in T cell responses, but lose sight of where this happens in the body. ... [Information of the supplier]
My name is Rick Speare and my aim at this site is to provide high quality information on diseases of amphibians with a focus on diseases of significance in wild populations. Much of the information deals with the diseases, particularly chytridiomycosis, associated with amphibian declines. I hope you enjoy visiting this site and using the material provided. ... [Information of the supplier]
The purpose of this weblog is to teach you about viruses and viral disease. This topic is not one that everyone understands, yet nearly everyone would like to. I was most disturbed when the Secretary of Health and Human Services, Tommy G. Thompson, referred to the anthrax bacillus as a virus. That incident crystallized in my mind the need to better educate the public about viruses. ... [Information of the supplier]
AMCA is a nonprofit organization that is dedicated to providing leadership, information and education leading to the enhancement of public health and quality of life through the suppression of mosquitoes. [Information of the supplier]
In 1997, parasitologists at the Universities of Alberta and Calgary decided to offer a joint undergraduate course on the Principles of Parasitism, with lectures given by live videoconference. It was decided to forego the traditional "sit-down-at-a-microscope" laboratory in favor of a lab that was completely web-based. This web site evolved as part of that project. Over the years we have had numerous requests from around the world for access to the web lab. As the site has evolved, it has become necessary to password-protect parts of the site that deal with our teaching function. We have decided to extract the basic laboratory component of the site and make it freely-accessible. The result is this site you are now viewing. ... [Information of the supplier]