The study of regulatory RNAs in the control of prokaryotic genomes has become a very active and rapidly growing field. New small and large noncoding RNA molecules continue to be discovered at a staggering rate in bacterial model organisms as well as in the transcriptomes of bacterial communities. Newly discovered structural and functional aspects of such RNAs have reached a degree of breadth that requires a meeting with a strong focus on bacterial RNA research to fully address the diversity of these new regulators of gene expression and bring together the scientists involved in these studies. Regulating with RNA in Bacteria was the first conference dedicated to this topic and premiered a forum for the presentation of cutting-edge advances and the latest perspectives in the areas of discovery, mechanisms and structure of bacterial riboregulators. This conference is the successor of two well-received previous meetings that were held in Berlin (2009) and San Juan (2011), and will be co-sponsored by DFG Program SPP1258 on Sensory and regulatory RNA in prokaryotes. We believe that the topic will attract many researchers from abroad and expect up to 250 participants. Aside from lectures by a number of international experts there will be additional oral presentations selected from submitted abstracts. There also will be sufficient time and space for poster presentations. Sessions will include small regulatory RNAs, riboswitches and RNA thermometers, RNA binding proteins, RNA structure, RNA localization & processing, CRISP/CASS, and RNA bioinformatics. ... [Information of the supplier]
SRS (sequence retrieval system) is one of the most powerful data browsing/retrieval tools available. SRS provides rapid, easy and user friendly access to the large volumes of diverse and heterogeneous Life Science data stored in more than 400 internal and public domain databases. It can be used to browse the various biological sequence and literature databases the EBI has available. ... [Information of the supplier]
BioMagResBank (BMRB) is the publicly-accessible depository for NMR results from peptides, proteins, and nucleic acids recognized by the International Society of Magnetic Resonance and by the IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy. In addition, BMRB provides reference information and maintains a collection of NMR pulse sequences and computer software for biomolecular NMR. Access to data in BMRB is free directly from its web site (URL http://www.bmrb.wisc.edu) and ftp site (ftp.bmrb.wisc.edu) and will remain so as public funding permits. The concept of a biomolecular NMR data bank was developed under a five-year research grant awarded to the University of Wisconsin-Madison from the National Library of Medicine, National Institutes of Health. ... [Information of the supplier]
The Bioinformatics Links Directory features curated links to molecular resources, tools and databases. All of the resources are free or available for a nominal fee. The links listed in this directory are selected on the basis of recommendations from bioinformatics experts in the field. We make every effort to list useful, well tested resources instead listing all tools. ... [Information of the supplier]
Many resources (e.g. Nature Reviews Genetics) offer a 10,000-foot view of the current trends in the field, reviews of various technologies, and guidelines on how to effectively design, analyze, and interpret experiments in human genetics and bioinformatics research. By comparison very few resources focus on the mundane, yet critical know-how for those on the ground actually doing the science (i.e. grad students, postdocs, analysts, and junior faculty). Getting Genetics Done aims to fill that gap by featuring software, code snippets, literature of interest, workflow philosophy, and anything else that can boost productivity and simplify getting things done in human genetics research. ... [Information of the supplier]
Individualised medicine based on patient genomes will have an enormous impact on healthcare. With breakthroughs in DNA sequencing technology, the number of sequenced genomes could reach >1 Million within 5–10 years. The simultaneous generation and integration of this associated molecular and clinical data will provide an unprecedentedly rich set of “big data” for basic research and translation. Integration of these data will provide new research opportunities, for example, through the identification of novel biomarkers or by enabling the identification of causal relationships in molecular biology through analysing complex datasets, but will also come with significant technical and bioethical challenges. This EMBL-Wellcome Genome Campus Conference on “Big Data in Biology & Health” will be held at EMBL Heidelberg, and will alternate between Heidelberg and Hinxton yearly to address the opportunities and challenges of “big data” analytics, advance basic research and explore translational opportunities. This timely interdisciplinary meeting aims to enable the European research community to participate in and help drive the future development of “big data” research, as well as raise further awareness for this new and relevant research direction in the life sciences. ... [Information of the supplier]
