BioMagResBank (BMRB) is the publicly-accessible depository for NMR results from peptides, proteins, and nucleic acids recognized by the International Society of Magnetic Resonance and by the IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy. In addition, BMRB provides reference information and maintains a collection of NMR pulse sequences and computer software for biomolecular NMR. Access to data in BMRB is free directly from its web site (URL http://www.bmrb.wisc.edu) and ftp site (ftp.bmrb.wisc.edu) and will remain so as public funding permits. The concept of a biomolecular NMR data bank was developed under a five-year research grant awarded to the University of Wisconsin-Madison from the National Library of Medicine, National Institutes of Health. ... [Information of the supplier]
The human genome seems to encode for not more than 30,000 to 40,000 proteins. A major challenge is to understand how posttranslational events, such as glycosylation, affect the activities and functions of these proteins in health and disease. The importance of protein glycosylation is becoming widely realized through studies on protein folding, protein localization and trafficking, protein solubility, biological half-life as well as studies on cell-cell interactions. The progressing Glycomics projects will dramatically accelerate the understanding of the roles of carbohydrates in cell communication and lead to novel therapeutic approaches for treatment of human disease. The MIT's magazine of innovation (January 21 2003) has identified Glycomics as one of the top ten technologies that will change the future. To support the upcoming Glycomics projects we [German Cancer Research Center (DKFZ), Heidelberg] focus our research activities on the development of bioinformatic tools and databases for glycobiology. ... [Information of the supplier]
ZFIN serves as the zebrafish model organism database. The long term goals for ZFIN are a) to be the community database resource for the laboratory use of zebrafish, b) to develop and support integrated zebrafish genetic, genomic and developmental information, c) to maintain the definitive reference data sets of zebrafish research information, d) to link this information extensively to corresponding data in other model organism and human databases, e) to facilitate the use of zebrafish as a model for human biology and f) to serve the needs of the research community. ... [Information of the supplier]
The Structural Genomics Consortium (SGC) is a not-for-profit organization that aims to determine the three dimensional structures of proteins of medical relevance, and place them in the public domain without restriction. The SGC operates out of the Universities of Oxford and Toronto and Karolinska Institutet, Stockholm. The SGC works on structures of proteins from its Target List of ~2,000 proteins, which comprises human proteins associated with diseases such as cancer, diabetes, inflammation, and genetic diseases, as well as proteins from human parasites such as those that cause malaria. Research at the SGC is divided into three areas: structural genomics of soluble proteins, structural genomics of integral membrane proteins, and structural chemistry of soluble proteins. ... [Information of the supplier]
Ensembl is a joint project between EMBL - European Bioinformatics Institute (EBI) and the Wellcome Trust Sanger Institute (WTSI) to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes. The Ensembl project aims to provide: accurate, automatic analysis of genome data, analysis and annotation maintained on the current data, presentation of the analysis to all via the web, distribution of the analysis to other bioinformatics laboratories. Ensembl will concentrate on vertebrate genomes, but other groups have adapted the system for use with plant and fungal genomes. ... [Information of the supplier, modified]
Welcome to DAVID Bioinformatics Resources 2003 – 2009. The Database for Annotation, Visualization and Integrated Discovery (DAVID). DAVID 2008 is the sixth version of our original web-accessible programs. DAVID now provides a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large list of genes. For any given gene list, DAVID tools are able to identify enriched biological themes, particularly GO terms; to discover enriched functional-related gene groups; to search for other functionally related genes; to list interacting proteins; and to link gene-disease associations. ... [Information of the supplier, modified]
BioCatalogue will provide a curated and comprehensive catalogue of biological web services, thereby enabling users (people and programs) to discover and use these services easily. It also aims to provide a platform with several (standardized) interfaces and a suite of tools for registration of services by the community of users as well as empower the community to extend and enhance the system. BioCatalogue will provide a centralized biological web services market place which will be accessible to the world as it will be searchable and indexable to search engines. BioCatalogue will provide a quality of service standard for biological web services thereby enabling services to be classified and checked for availability, reliability and other quality measures. BioCatalogue is a BBSRC funded project and has been running since 1st June 2008. The project is a joint venture between the EMBL-EBI (led by Rodrigo Lopez) and the myGrid project at the University of Manchester (led by Carole Goble). ... [Information of the supplier]
ModelDB is a curated database of published models in the broad domain of computational neuroscience. It addresses the need for access to such models in order to evaluate their validity and extend their use. It can handle computational models expressed in any textual form, including procedural or declarative languages (e.g. C++, XML dialects) and source code written for any simulation environment. The model source code doesn't even have to reside inside ModelDB; it just has to be available from some publicly accessible online repository or WWW site. ModelDB is curated in order to maximize the scientific utility of its contents. The ideal model entry would contain "original" (author-written) source code, especially if it works and reproduces at least one figure from a published article. Original source code has tremendous value because it is what the authors used to generate the simulation results from which they derived their published insights and conclusions. High quality "third party" re-implementations of published models are also relevant, especially those involving models that are of wide interest. ... [Information of the supplier]
Dryad is an international repository of data underlying peer-reviewed articles in the basic and applied biosciences. Dryad enables scientists to validate published findings, explore new analysis methodologies, repurpose data for research questions unanticipated by the original authors, and perform synthetic studies. Dryad is being developed by the National Evolutionary Synthesis Center and the University of North Carolina Metadata Research Center, in coordination with a large group of Journals and Societies in evolutionary biology and ecology. The National Evolutionary Synthesis Center is a joint effort of Duke University, the University of North Carolina, and North Carolina State University. ... [Information of the supplier, modified]
PlutoF provides cloud database and computing services for the taxonomical, ecological, phylogenetical, etc. research. The purpose of the platform is to provide synergy through common modules for the classifications, taxon names, analytical tools, etc. It allows to address integrated questions in ecology and coevolution of taxa. Different types of the species occurrences, viz. preserved specimens, DNA sequences, human observations, references can be stored in PlutoF as well. PlutoF has no restrictions on taxon and geographic coverage and therefore can be used for the databasing interacting taxa. It includes also collection management module. ... [Information of the supplier]
