This interdisciplinary symposium will highlight exciting new insights into the molecular principles that govern the functional framework of genomes in space and time. The meeting program will cover all levels of organisational complexity, from DNA to chromosomes, and in model systems ranging from bacteria to humans. A particular highlight will be the integration of discoveries made in different disciplines, including cell and molecular biology, biophysics, modelling, structural biology and biochemistry. ... [Information of the supplier]
The Allen Brain Atlas (ABA) is an interactive, genome-wide image database of gene expression in the mouse brain. A combination of RNA in situ hybridization data, detailed Reference Atlases and informatics analysis tools are integrated to provide a searchable digital atlas of gene expression. Together, these resources present a comprehensive online platform for exploration of the brain at the cellular and molecular level. ... [Information of the supplier]
The goal of the Nucleic Acid Database Project (NDB) is to assemble and distribute structural information about nucleic acids. The NDB was founded in 1992 by Helen M. Berman, Rutgers University, Wilma K. Olson, Rutgers University, and David Beveridge, Wesleyan University. In addition, Anke Gelblin, Tamas Demeny, S. -H. Hsieh, A.R. Srinivasan, and Bohdan Schneider were members of the original NDB project team. The NDB Project is funded by the National Science Foundation and the Department of Energy. The NDB maintains the mmCIF Web site. mmCIF (macromolecular Crystallographic Information File) is the IUCr-approved data representation for macromolecular structures. ... [Information of the supplier]
The NCBI Entrez Genome Project database is intended to be a searchable collection of complete and incomplete large-scale sequencing, assembly, annotation, and mapping projects for cellular organisms. The database is organized into organism-specific overviews that function as portals from which all projects in the database pertaining to that organism can be browsed and retrieved. ... [Information of the supplier, modified]
SINEBase is a database of SINEs and a toolset for their identification and analysis.Short interspersed elements (SINEs) are repetitive DNA sequences invading the genomes of eukaryotes. They can amount to more than 10% of the genome in some species but are missing from other ones. While these genomic parasites can be deleterious to the cell, the long-term being in the genome has made SINEs a valuable factor of genetic variation providing regulatory elements for gene expression, alternative splice sites, polyadenylation signals, and even functional RNA genes. ... [Information of the supplier]
There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Several human diseases, including cancer, have already been linked to DNA replication stress, a term that refers to perturbations in DNA replication. Therefore, a better understanding of how cells respond to this will help us understand disease development and responses to therapy. By bringing together experts in the basic biology of DNA replication and DNA replication stress, this symposium aims to fuel further progress in these important fields. ... [Information of the supplier]
This site provides access to raw data from various QTL (quantitative trait loci) studies using rodent inbred line crosses. Data are available in the .csv format used by R/qtl and pseudomarker programs. In some cases analysis scripts and/or results are posted to accompany the data. These data are provided as a courtesy to the genetic mapping community and may be used for purposes of developing or testing new analysis methods or software and for meta-analysis of quantitative traits. The authors of the datasets retain individual ownership of the data. We request, as a courtesy to the authors, that you alert them in advance of any publications that result from reanalysis of these data or obtain permission prior to redistribution of data or results. In all data sets and files, the marker locations have been translated to Cox build 37 coordinates unless otherwise stated. ... [Information of the supplier]
The annual President's Symposium will be held on August 17-20, 2015 at Island Wood on Bainbridge Island near Seattle, WA. The meeting will bring together people working on both molecular and evolutionary aspects of chromosome evolution in order to stimulate exchange of ideas between scientists with different perspectives. The meeting will start with a reception on the evening of August 17, followed by two full days of talks, and conclude with breakfast on the morning of August 20. Mark Kirkpatrick will present the Key Distinguished Lecture on the theory surrounding chromosome evolution. ... [Information of the supplier]
For those scientists interested in RNA, and its diverse biological roles, the RNA World website has been set up, which collects RNArelated Internet resources. It provides links to databases of sequences, secondary structures, and coordinates and images of three-dimensional structures to other web tools, software, books, tutorials, meetings and to the RNA prototype newsgroup archive. ... [Information of the supplier]
The Vienna RNA Package consists of a C code library and several stand-alone programs for the prediction and comparison of RNA secondary structures. [Information of the supplier]