This interdisciplinary symposium will highlight exciting new insights into the molecular principles that govern the functional framework of genomes in space and time. The meeting program will cover all levels of organisational complexity, from DNA to chromosomes, and in model systems ranging from bacteria to humans. A particular highlight will be the integration of discoveries made in different disciplines, including cell and molecular biology, biophysics, modelling, structural biology and biochemistry. ... [Information of the supplier]
There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Several human diseases, including cancer, have already been linked to DNA replication stress, a term that refers to perturbations in DNA replication. Therefore, a better understanding of how cells respond to this will help us understand disease development and responses to therapy. By bringing together experts in the basic biology of DNA replication and DNA replication stress, this symposium aims to fuel further progress in these important fields. ... [Information of the supplier]
GBOL - German Barcode of Life: → Inventarisierung und genetische Charakterisierung der Tiere, Pflanzen und Pilze Deutschlands. Das GBOL-Projekt hat das Ziel die Artenvielfalt aller deutschen Tiere, Pilze und Pflanzen anhand ihres genetischen DNA-Barcodes (Fingerabdrucks) zu erfassen. Damit übernimmt Deutschland als Wissenschaftsnation eine führende Rolle in einem internationalen Konsortium aus Naturkundemuseen, Zoos, Herbarien, Forschungseinrichtungen und staatlichen Institutionen, die den Aufbau einer "DNA Barcode Bibliothek des Lebens" (pdf) zum Ziel haben. Bis heute sind weltweit ~1,5 Millionen DNA Barcodes von ~145.000 beschriebenen Arten in der BOLD Datenbank erfasst (Stand: Dez. 2011). GBOL ist ein deutschlandweites Netzwerk aus verschiedenen Naturkundemuseen und anderen Biodiversitätsforschungsinstituten. Die GBOL Partner stellen ihre professionelle taxonomische Expertise und ihre bereits existierende Infrastruktur (Sammlungen/Biobanken, Datenbanken, Bioinformatik-Plattformen und Labore) zur Verfügung, um umfassend und flächendeckend die Tier- und Pflanzenarten Deutschlands zu sammeln, zu katalogisieren, wissenschaftlich zu beschreiben, zu sequenzieren und in die globale Referenz-Barcode Datenbank „BOLD“ einzuspeisen. Die morphologische Artidentifikation wird zunächst durch spezialisierte Experten (Taxonomen) erfolgen, die ihr Wissen über die Morphologie, Ökologie, Reproduktionsmodus und Lebenszyklus bestimmter Taxa einbringen. Mit modernsten DNA Sequenziermethoden wird in einem zweiten Schritt der DNA Barcode entschlüsselt. Der Artensteckbrief wird mit dem DNA Barcode verknüpft und in einer öffentlich zugänglichen DNA Barcode Referenz-Datenbank verfügbar gemacht. Die professionellen GBOL Taxonomen sind bei dieser Aufgabe besonders auf die tatkräftige Unterstützung und Kooperation von ehrenamtlichen Taxon-Experten aus ganz Deutschland angewiesen. ... [Information des Anbieters]
The study of regulatory RNAs in the control of prokaryotic genomes has become a very active and rapidly growing field. New small and large noncoding RNA molecules continue to be discovered at a staggering rate in bacterial model organisms as well as in the transcriptomes of bacterial communities. Newly discovered structural and functional aspects of such RNAs have reached a degree of breadth that requires a meeting with a strong focus on bacterial RNA research to fully address the diversity of these new regulators of gene expression and bring together the scientists involved in these studies. Regulating with RNA in Bacteria was the first conference dedicated to this topic and premiered a forum for the presentation of cutting-edge advances and the latest perspectives in the areas of discovery, mechanisms and structure of bacterial riboregulators. This conference is the successor of two well-received previous meetings that were held in Berlin (2009) and San Juan (2011), and will be co-sponsored by DFG Program SPP1258 on Sensory and regulatory RNA in prokaryotes. We believe that the topic will attract many researchers from abroad and expect up to 250 participants. Aside from lectures by a number of international experts there will be additional oral presentations selected from submitted abstracts. There also will be sufficient time and space for poster presentations. Sessions will include small regulatory RNAs, riboswitches and RNA thermometers, RNA binding proteins, RNA structure, RNA localization & processing, CRISP/CASS, and RNA bioinformatics. ... [Information of the supplier]
This symposium focuses on the interface of ecology and evolutionary genetics, with special emphasis placed on the interaction between organisms as a basis for understanding ecological adaptation. New sequencing-based methods are bridging the gap between modern genetics and systems-level ecological studies. This is paralleled by dramatic improvements in imaging and remote sensing, with which one can capture both spatial and temporal components of dynamic interactions between individuals and their natural environment. ... [Information of the supplier]
Individualised medicine based on patient genomes will have an enormous impact on healthcare. With breakthroughs in DNA sequencing technology, the number of sequenced genomes could reach >1 Million within 5–10 years. The simultaneous generation and integration of this associated molecular and clinical data will provide an unprecedentedly rich set of “big data” for basic research and translation. Integration of these data will provide new research opportunities, for example, through the identification of novel biomarkers or by enabling the identification of causal relationships in molecular biology through analysing complex datasets, but will also come with significant technical and bioethical challenges. This EMBL-Wellcome Genome Campus Conference on “Big Data in Biology & Health” will be held at EMBL Heidelberg, and will alternate between Heidelberg and Hinxton yearly to address the opportunities and challenges of “big data” analytics, advance basic research and explore translational opportunities. This timely interdisciplinary meeting aims to enable the European research community to participate in and help drive the future development of “big data” research, as well as raise further awareness for this new and relevant research direction in the life sciences. ... [Information of the supplier]
The main objective of this conference is to bring people together from diverse disciplines to exchange ideas, promote cross-disciplinary collaborations and to form a synthesis of appropriate systems-level approaches. The meeting is therefore purposely broad to cover all aspects of genomics to systems biology, a unique combination that is highly appreciated by the participants. Over the past decade, this EMBO conference has therefore served as an important venue in helping to shape the field, or to be more precise to help generate a community of scientists that come from very diverse disciplines, each with the common goal to understand the systems level properties of their system of interest. Topics: Transcription, chromatin and nucleosomes; 3D structure, epigenetics; Post-transcriptional regulation and non-coding RNA; Proteomics, protein-protein interaction networks, metabolites; Genetic interaction networks; Single cell variation, biological noise; Systems Genetics, genotype to phenotype; Human genome variation; Data integration, Modelling and prediction. ... [Information of the supplier]
The principal objective of this conference series is to provide an international forum for cutting edge research in chromatin and epigenetics. This conference provides “the focal hub” for people to present their research and exchange ideas in a European venue. The organising team assembles top speakers covering the latest advances in the field, incorporating diversity in every sense (gender, geography etc). The overarching goal of this conference series is to cover chromatin regulation, chromatin dynamics, signalling to chromatin, nuclear architecture and dynamics, developmental epigenetics, epigenomics, epigenetics and human diseases, genome stability, environmental epigenetics, and transgenerational inheritance. We also include talks on latest approaches for studying these biological questions, including functional genomics, system biology and super resolution microscopy. ... [Information of the supplier]
The goal of this symposium is to promote interactions between researchers studying neural circuits both in traditional model systems (worm, fly, fish, mouse), in humans, and in diverse, emerging models to (i) discuss the origins, commonalities and differences of animal nervous systems, (ii) highlight the spectacular capabilities of neural circuits to control animal behaviour, and (iii) reflect on how technological innovations will open up new possibilities to understand and repair the nervous system. By bringing together a unique and eclectic mix of scientists studying nervous systems from the molecular to the psychological level, this symposium should stimulate novel cross-fertilisation of ideas and methodologies to understand neural circuit structure and function. ... [Information of the supplier]
This symposium will build on the first meeting which took place in 2016. Microbiologists and immunologists will again come together to provide different viewpoints on the same problems in joint sessions. While maintaining continuity in topics, the meeting concept will be evolved by introducing novel sessions on bacterial defenses against innate immunity, an area prominently covered by abstract submissions in the 2016 meeting, and on fungus host interactions, an under-researched area of great medical importance ... [Information of the supplier]
