The Allen Brain Atlas (ABA) is an interactive, genome-wide image database of gene expression in the mouse brain. A combination of RNA in situ hybridization data, detailed Reference Atlases and informatics analysis tools are integrated to provide a searchable digital atlas of gene expression. Together, these resources present a comprehensive online platform for exploration of the brain at the cellular and molecular level. ... [Information of the supplier]
The goal of the Nucleic Acid Database Project (NDB) is to assemble and distribute structural information about nucleic acids. The NDB was founded in 1992 by Helen M. Berman, Rutgers University, Wilma K. Olson, Rutgers University, and David Beveridge, Wesleyan University. In addition, Anke Gelblin, Tamas Demeny, S. -H. Hsieh, A.R. Srinivasan, and Bohdan Schneider were members of the original NDB project team. The NDB Project is funded by the National Science Foundation and the Department of Energy. The NDB maintains the mmCIF Web site. mmCIF (macromolecular Crystallographic Information File) is the IUCr-approved data representation for macromolecular structures. ... [Information of the supplier]
The NCBI Entrez Genome Project database is intended to be a searchable collection of complete and incomplete large-scale sequencing, assembly, annotation, and mapping projects for cellular organisms. The database is organized into organism-specific overviews that function as portals from which all projects in the database pertaining to that organism can be browsed and retrieved. ... [Information of the supplier, modified]
SINEBase is a database of SINEs and a toolset for their identification and analysis.Short interspersed elements (SINEs) are repetitive DNA sequences invading the genomes of eukaryotes. They can amount to more than 10% of the genome in some species but are missing from other ones. While these genomic parasites can be deleterious to the cell, the long-term being in the genome has made SINEs a valuable factor of genetic variation providing regulatory elements for gene expression, alternative splice sites, polyadenylation signals, and even functional RNA genes. ... [Information of the supplier]
There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Several human diseases, including cancer, have already been linked to DNA replication stress, a term that refers to perturbations in DNA replication. Therefore, a better understanding of how cells respond to this will help us understand disease development and responses to therapy. By bringing together experts in the basic biology of DNA replication and DNA replication stress, this symposium aims to fuel further progress in these important fields. ... [Information of the supplier]
Completed in 2003, the Human Genome Project (HGP) was a 13-year project coordinated by the U.S. Department of Energy and the National Institutes of Health. During the early years of the HGP, the Wellcome Trust (U.K.) became a major partner; additional contributions came from Japan, France, Germany, China, and others. See our history page for more information. Project goals were to identify all the approximately 20,000-25,000 genes in human DNA, determine the sequences of the 3 billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, transfer related technologies to the private sector, and address the ethical, legal, and social issues (ELSI) that may arise from the project. Though the HGP is finished, analyses of the data will continue for many years. Follow this ongoing research on our Progress page. ... [Information of the supplier]
DDBJ (DNA Data Bank of Japan) began DNA data bank activities in earnest in 1986 at the National Institute of Genetics (NIG). From the beginning, DDBJ has been functioning as one of the International DNA Databases, including EBI in Europe and NCBI in the USA as the two other members. Consequently, we have been collaborating with the two data banks through exchanging data and information on Internet and by regularly holding two meetings, the International DNA Data Banks Advisory Meeting and the International DNA Data Banks Collaborative Meeting. DDBJ is the sole DNA data bank in Japan, which is officially certified to collect DNA sequences from researchers and to issue the internationally recognized accession number to data submitters. We collect data mainly from Japanese researchers, but of course accept data and issue the accession number to researchers in any other countries. Since we exchange the collected data with EMBL/EBI and GenBank/NCBI on a daily basis, the three data banks share virtually the same data at any given time. We also provide worldwide many tools for data retrieval and analysis developed by at DDBJ and others. ... [Information of the supplier]
A database is a model of a piece of the world. RegulonDB in this sense is a model of the complex regulation of transcription initiation or regulatory network of the cell, on the one hand. On the other hand, it is also a model of the organization of the genes in transcription units, operons and simple and complex regulons. In this sense, RegulonDB is a computational model of mechanisms of transcriptional regulation. ... [Information of the supplier]
Cyanobacteria carry a complete set of genes for oxygenic photosynthesis, which is the most fundamental life process on the earth. This organism is also interesting from an evolutional viewpoint, for it was born in a very ancient age and has survived in various environments. Chloroplast is believed to have evolved from cyanobacterial ancestors which developed an endosymbiontic relationship with a eukaryotic host cell. CyanoBase provides an easy way of accessing the sequences and all-inclusive annotation data on the structures of the cyanobacterial genomes. ... [Information of the supplier]
Saccharomyces Genome Database is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast. (...) SGD contains the sequences of yeast genes and proteins; descriptions and classifications of their biological roles, molecular functions, and subcellular localizations; links to literature information; links to functional genomics datasets; and tools for analysis and comparison of sequences. The SGD Home page is the main entry point for the database. SGD is aimed at scientists; collected information about yeast for the non-scientist can be found at the Yeast Virtual Library. SGD does not collect medical information, and SGD curators cannot answer health-related questions. ... [Information of the supplier]
