The human genome seems to encode for not more than 30,000 to 40,000 proteins. A major challenge is to understand how posttranslational events, such as glycosylation, affect the activities and functions of these proteins in health and disease. The importance of protein glycosylation is becoming widely realized through studies on protein folding, protein localization and trafficking, protein solubility, biological half-life as well as studies on cell-cell interactions. The progressing Glycomics projects will dramatically accelerate the understanding of the roles of carbohydrates in cell communication and lead to novel therapeutic approaches for treatment of human disease. The MIT's magazine of innovation (January 21 2003) has identified Glycomics as one of the top ten technologies that will change the future. To support the upcoming Glycomics projects we [German Cancer Research Center (DKFZ), Heidelberg] focus our research activities on the development of bioinformatic tools and databases for glycobiology. ... [Information of the supplier]
Sequencing of the human genome has opened the way and provided the impetus for building a comprehensive picture of a mammalian cell. Significant efforts are underway in the fields of genomics and proteomics to identify all genes and proteins in a given organism. The goal is a complete map of the genes, gene products and their interaction networks in a functioning cell. The next step in establishing a comprehensive picture of a cell will be to tie the cell's metabolome into the rapidly developing genomic and proteomic maps. A cell's metabolome, however, is such an enormous and complex entity that characterizing it can only be approached in sections. This consortium is now proposing to focus on the lipid section of the metabolome by developing an integrated metabolomic system capable of characterizing the global changes in lipid metabolites ("lipidomics"). Our consortium has developed a Lipid Metabolites and Pathways Strategy, termed LIPID MAPS, that applies a global integrated approach to the study of lipidomics. ... [Information of the supplier]
The official database of Japanese Conference on the Biochemistry of Lipids (JCBL). "LIPID BANK for web" is an open, publicly free database of natural lipids including fatty acids, glycerolipids, sphingolipids, steroids, and various vitamins. The database contains more than 6000 unique molecular structures (ChemDraw cdx format, MDL MOL format), their lipid names (common name, IUPAC), spectral information (mass, UV, IR, NMR and others), and most importantly, literature information. The database lists natural lipids only, and all molecular information is manually curated and approved by experts in lipid research. ... [Information of the supplier]
This site lists all substances and their properties which are reported on in the indexed Landolt-Börnstein volumes. In total, 160 000 organic and inorganic compounds are described by names, molecular structures, chemical abstract numbers and other identifiers. Properties are directly linked to the full documents at Springerlink. Landolt-Börnstein citations are given as "Vol. LB-Group/Volume Chapter: number [, page]: document title" and have a hyperlink to the full-text of the document containing the substance. The short identifier of the LB volume leads to a complete denotation of the reference with a direct link to the respective volume. For several compounds crosslinks to some derivatives are provided, e.g. isotope-marked compounds, hydrates and hydrochlorides. For benzenamine (aniline) for example there is a direct link to the related compounds benzenamine-d7 and aniline hydrochloride/hydrobromide/hydroiodide. Additionally, EINECS numbers (European Inventory of Existing Commercial Chemical Substances) are provided if available. Compounds are linked to NIMS (National Institute for Materials Science) data where disposable. ... [Information of the supplier]
MassBank is the first public repository of mass spectral data for sharing them among scientific research community. MassBank data are useful for the chemical identification and structure elucidation of chemical compounds detected by mass spectrometry. This website counts with the following features: a) distributed database, b) high precision and accurate mass spectra of primary metabolites and secondary metabolites, c) mass spectral search by exact m/z and browsing interface and d) search for merged spectra. A merged spectrum is generated from spectra of the identical compound measured in different CID conditions. The MassBank Record for each merged spectrum includes information of its original spectra. ... [Information of the supplier, modified]
Humans perceive numerous compounds as bitter. The bitterness of a compound often provides a hint to its potential toxicity, and aversion from bitterness helps refrain from consuming poisons. Well known example is strychnine. Some other bitter compounds, such as caffeine, while toxic in high dosages, are palatable and is consumed in large quantities. The amount of bitter compounds is estimated in thousands. But what are these compounds? How similar or different are their chemical properties? Do they act on the same or on different receptors? Is it possible to predict bitterness of a molecule? To enable investigation into these intriguing questions, we established BitterDB, a free and searchable database of bitter compounds. BitterDB currently holds over 550 bitter compounds obtained from the literature and from Merck index and their associated 25 human bitter taste receptors (hT2Rs). BitterDB provides several ways to investigate the bitter world: search for bitter compounds by different criteria, search for bitter molecules with structure similar to a query compound, blast bitter receptors and more. ... [Information of the supplier]
The “Yeast Lipid Conference” (YLC) is an international scientific meeting held every second year (typically in late May) to promote free discussion between scientists working on or interested in all aspects of yeast lipids. The 12th edition of YLC will be held in Ghent, Belgium from the 20th till the 22nd of May 2015. It will start on Wednesday afternoon with registration followed by the opening lecture, and an evening reception. The following two days will be seminars by invited guests with some speakers chosen from submitted abstracts, poster sessions, and social events. This is the first time the conference will be hosted in Belgium and we are pleased that Ghent will be the location for this. All lectures will take place at the Faculty of Bio-Science engineering at Ghent University, which is located at walking distance from the historical city centre of Ghent. It is worth spending time before or after the meeting to discover this sparkling city and visit other points of interest in Belgium. ... [Information of the supplier]
On behalf of the Plant Oxygen Group, the Local Organizing Committee is pleased to invite you to attend the “12th International Conference on Reactive Oxygen and Nitrogen Species in Plants: from model systems to field” which will be held in Verona, Italy on June 24th-26th 2015. The Plant Oxygen Group (POG) Conference, supported by the Society for Free Radical Research (SFRR-Europe), is a great forum for discussion and for the effective exchange of information and ideas on every aspect regarding reactive oxygen and nitrogen species metabolism, action and signaling in plants. The Conference aims also to provide a dynamic interface between academic research and field applications, and represents an important opportunity for everyone in the field, especially promoting early career scientist participation. The scientific program will include several oral communications by young promising scientists - selected from abstracts- next to lectures by top scientists, facilitating discussion among participants in a friendly and stimulating environment. ... [Information of the supplier]
We are pleased to announce that the XIXth International meeting on "Oxygen binding and sensing proteins" will take place at the University of Hamburg from Sunday, 11 September to Wednesday, 14 September 2016. The meeting will bring together researchers from the fields of biochemistry, biophysics, structural biology, physiology, genetics, and evolutionary biology working who work with any types of proteins that function in oxygen binding, sensing or processing. The meeting addresses researchers of all levels of their career, from students to professors. ... [Information of the supplier]
The EMBO conference ‘The nitrogen nutrition of plants - Nitrogen2016’ will be the third international symposium on the nitrogen nutrition of plants, following Nitrogen2013 in Puerto Varas (Chile) and Nitrogen2010 in Inuyama-city (Japan) and the founder meeting Nitrogen2007 in Lancaster (UK). At a time when improved nitrogen use efficiency by crops is clearly identified as a major issue for sustainable agriculture, the main objective of this conference will be to review recent progress in the understanding of molecular, physiological and developmental processes involved in the nitrogen nutrition of plants. Nitrogen2016 will also aim at fostering exchanges and collaborations within the rapidly expanding scientific community interested in these topics. ... [Information of the supplier]
