The purpose of the BioSamples database is to provide unified storage and access to information about biological samples. These samples may have investigation information stored in other databases (e.g. sequencing, structure, expression). Physical samples may also be available for further study from suppliers. The definition of a sample is flexible. Most samples are straightforward, such as tissue from an individual organism. However, a sample can also be an environmental sample (e.g. for meta-genomic analysis), a hybrid between two species, infected tissue, etc. Within the BioSamples Database, collections of samples are managed as "submission". Each submission is one SampleTab format file emailed to biosamples@ebi.ac.uk. Some highly-curated and highly-referenced submissions may become "reference samples", for example the ENCODE cell lines. These are samples that are of particular interest and have datasets from multiple technologies associated with them. ... [Information of the supplier]
EBIMed is a web application that combines Information Retrieval and Extraction from Medline. EBIMed finds Medline abstracts in the same way PubMed does. Then it goes a step beyond and analyses them to offer a complete overview on associations between UniProt protein/gene names, GO annotations, Drugs and Species. The results are shown in a table that displays all the associations and links to the sentences that support them and to the original abstracts. You can type term queries in the text box provided following the syntax conventions that can be found here. Your terms will be looked up throughout Medline and several abstracts will thus be retrieved and analysed. In the simple interface the higher limit is 500 to make the process quick. You can set a higher limit through the Advanced Search interface. By selecting relevant sentences and highlighting the biomedical terminology EBIMed enhances your ability to acquire knowledge, relate facts, discover implications and, overall, have a good overview economizing the effort in reading. ... [Information of the supplier, modified]
The Executive Committee of FEBS has awarded the FEBS Congress for 2013 to the Russian Biochemical Society. It will be located in St. Petersburg, July 6th – 11th 2013 under the Congress Presidency of Professor Vladimir Skulachev with Professor Sir Richard Roberts as Chairman of the International Advisory Board. The Congress Theme is “Mechanisms in Biology” and we are seeking to build a powerful and diverse program to support this key theme. Symposia presently under consideration include: Immunology, RNA, Carbohydrate Biochemistry, Stem Cell Biology, Mechanisms of Proteolysis, Bacteriology, Bioinformatics, & Techniques of Biochemistry. A total of 37 symposia will be included in the program. We are expecting to have a strong cohort of keynote and symposium speakers from Europe, USA, Japan and other countries. ... [Information of the supplier]
Today, vast amounts of protein-small molecule binding sites can be found in the Protein Data Bank (PDB). Exhaustive comparison of them is computationally demanding, but useful in the prediction of protein functions and drug discovery. We proposed a tremendously fast algorithm called "SketchSort" that enables the enumeration of similar pairs in a huge number of protein-ligand binding sites. We conducted all-pair similarity searches for 3.4 million known and potential binding sites using the proposed method and discovered over 24 million similar pairs of binding sites. We present the results as a relational database Pocket Similarity Search using Multiple-Sketches (PoSSuM), which includes all the discovered pairs with annotations of various types (e.g., CATH, SCOP, EC number, Gene ontology). PoSSuM enables rapid exploration of similar binding sites among structures with different global folds as well as similar ones. Moreover, PoSSuM is useful for predicting the binding ligand for unbound structures. Basically, the users can search similar binding pockets using two search modes: i) "Search K" is useful for finding similar binding sites for a known ligand-binding site. Post a known ligand-binding site (a pair of "PDB ID" and "HET code") in the PDB, and PoSSuM will search similar sites for the query site; ii) "Search P" is useful for predicting ligands that potentially bind to a structure of interest. Post a known protein structure (PDB ID) in the PDB, and PoSSuM will search similar known-ligand binding sites for the query structure. ... [Information of the supplier]
Rhea is a reaction database, where all reaction participants (reactants and products) are linked to the ChEBI database (Chemical Entities of Biological Interest) which provides detailed information about structure, formula and charge. Rhea provides built-in validations that ensure both elemental and charge balance of the reactions. We have populated the database with the reactions found in the EC list (and in the IntEnz and ENZYME databases), extending it with additional known reactions of biological interest. While the main focus of Rhea is enzyme-catalysed reactions, other biochemical reactions (including those that are often termed "spontaneous") also are included. Rhea is a manually annotated resource and it provides: a)Stable reaction identifiers for each of its reactions. These identifiers are independent of EC numbers but are linked to EC numbers via cross-references; b)Directionality information if the physiological direction of the reaction is known; c)The possibility to link several reactions together to form complex reactions. This feature can also be used to split reactions into partial reactions; d)Extensive cross-references to other resources including enzyme-catalysed and other metabolic reactions, such as the EC list (in IntEnz), KEGG, MetaCyc and UniPathway; e)Chemical substructure and similarity searches on compounds in Rhea, thereby allowing reactions to be found where similar compounds are involved. The database is extensively cross-referenced. Reactions are currently linked to the EC list, KEGG and MetaCyc, and the reactions will be used in the IntEnz database and in all relevant UniProtKB entries. Furthermore, the reactions will also be used in the UniPathway database to generate pathways and metabolic networks. ... [Information of the supplier]
The scientific program for Signalling 2013 - from Structure to Function, is designed to represent the cutting edge of modern signal transduction research. By including diverse, yet interrelated, topics this keystone meeting will demonstrate how cell signalling continues to underpin key advances in biological and medical research in the 21st century. Topics: Second messengers, REDOX signalling, Small molecule inhibitors, Inflammation, Cancer, Ubiquitin, Lipid and protein kinases and Ion channels. ... [Information of the supplier]
SCRIPDB is a chemical structure database designed to make this metadata accessible. We index public-domain chemical information contained in U.S. patents, and provide the full patent text, reactions, and relationships described within any individual patent, as well as the original CDX, MOL, and TIFF files. SCRIPDB may be searched by exact chemical structure, substructure, or molecular similarity and the results may be restricted to patents describing synthetic routes. SCRIPDB was first developed by Abraham Heifets and Igor Jurisica and is maintained by the Jurisica Lab at the Ontario Cancer Institute and the University of Toronto. ... [Information of the supplier, modified]
On behalf of the Organising Committee it is our great pleasure to invite you to Perth, Western Australia, to participate in the 9th IsoEcol Conference. The conference will be held 3-8 August 2014 at The University Club at The University of Western Australia, on the shores of the beautiful Swan River. IsoEcol 9 will bring together a mix of international and Australian researchers from universities, industry and government with interests in the development and application of stable isotope techniques to the ecological sciences. ... [Information of the supplier]
As President of the International Union of Photobiology, IUPB, as Chairwoman of the Organizing Committee and as Chairman of the Local Organizing Committee, we invite you to join us during the 16th International Congress on Photobiology to be held in the City of Córdoba in Argentina in September (8th to 12th) 2014, in the Campus of the University. This congress is organized every five years with the last one in Düsseldorf, Germany, in 2009. The Congress will address all areas of Photobiology such as photosensors in Archaea, Bacteria and Eucaria, photosynthesis including antennas and reaction centres, photomovement, photomorphogenesis, cryptochromes, LOV, BLUF and retinal proteins and domains, vision, circadian rhythms, environmental photobiology, UV influence on plankton, UV damage, protection and repair of DNA, photoreceptors in extremophiles (at high altitudes and in the Antarctic and Arctic regions), photoaging, photocarcinogenesis, photomedicine, synthetic and natural photosensitizers, photodynamic therapy, PUVA, vitiligo, molecular basis of the medical uses of lamps and lasers, artificial tanning, optogenetics, optical technology, photophysics and photochemistry of natural compounds, modelling photosynthesis with man-made compounds, and others. Sessions will be organized in several of these areas. ... [Information of the supplier]
We invite you to take part in the II International Interdisciplinary Conference "Adaptation Strategies of Living Systems", which will be held May 12-17, 2014 in a comfortable place of the Crimea, in the Novy Svet, Ukraine. Our conference is traditionally an effective interdisciplinary platform to bring together scientists from various research institutes and universities, engineers and managers, industrial organizations and companies working in biology, ecology and biomedical sciences. ... [Information of the supplier]