SRS (sequence retrieval system) is one of the most powerful data browsing/retrieval tools available. SRS provides rapid, easy and user friendly access to the large volumes of diverse and heterogeneous Life Science data stored in more than 400 internal and public domain databases. It can be used to browse the various biological sequence and literature databases the EBI has available. ... [Information of the supplier]
BioMagResBank (BMRB) is the publicly-accessible depository for NMR results from peptides, proteins, and nucleic acids recognized by the International Society of Magnetic Resonance and by the IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy. In addition, BMRB provides reference information and maintains a collection of NMR pulse sequences and computer software for biomolecular NMR. Access to data in BMRB is free directly from its web site (URL http://www.bmrb.wisc.edu) and ftp site (ftp.bmrb.wisc.edu) and will remain so as public funding permits. The concept of a biomolecular NMR data bank was developed under a five-year research grant awarded to the University of Wisconsin-Madison from the National Library of Medicine, National Institutes of Health. ... [Information of the supplier]
The Bioinformatics Links Directory features curated links to molecular resources, tools and databases. All of the resources are free or available for a nominal fee. The links listed in this directory are selected on the basis of recommendations from bioinformatics experts in the field. We make every effort to list useful, well tested resources instead listing all tools. ... [Information of the supplier]
Many resources (e.g. Nature Reviews Genetics) offer a 10,000-foot view of the current trends in the field, reviews of various technologies, and guidelines on how to effectively design, analyze, and interpret experiments in human genetics and bioinformatics research. By comparison very few resources focus on the mundane, yet critical know-how for those on the ground actually doing the science (i.e. grad students, postdocs, analysts, and junior faculty). Getting Genetics Done aims to fill that gap by featuring software, code snippets, literature of interest, workflow philosophy, and anything else that can boost productivity and simplify getting things done in human genetics research. ... [Information of the supplier]
Individualised medicine based on patient genomes will have an enormous impact on healthcare. With breakthroughs in DNA sequencing technology, the number of sequenced genomes could reach >1 Million within 5–10 years. The simultaneous generation and integration of this associated molecular and clinical data will provide an unprecedentedly rich set of “big data” for basic research and translation. Integration of these data will provide new research opportunities, for example, through the identification of novel biomarkers or by enabling the identification of causal relationships in molecular biology through analysing complex datasets, but will also come with significant technical and bioethical challenges. This EMBL-Wellcome Genome Campus Conference on “Big Data in Biology & Health” will be held at EMBL Heidelberg, and will alternate between Heidelberg and Hinxton yearly to address the opportunities and challenges of “big data” analytics, advance basic research and explore translational opportunities. This timely interdisciplinary meeting aims to enable the European research community to participate in and help drive the future development of “big data” research, as well as raise further awareness for this new and relevant research direction in the life sciences. ... [Information of the supplier]
ModelDB is a curated database of published models in the broad domain of computational neuroscience. It addresses the need for access to such models in order to evaluate their validity and extend their use. It can handle computational models expressed in any textual form, including procedural or declarative languages (e.g. C++, XML dialects) and source code written for any simulation environment. The model source code doesn't even have to reside inside ModelDB; it just has to be available from some publicly accessible online repository or WWW site. ModelDB is curated in order to maximize the scientific utility of its contents. The ideal model entry would contain "original" (author-written) source code, especially if it works and reproduces at least one figure from a published article. Original source code has tremendous value because it is what the authors used to generate the simulation results from which they derived their published insights and conclusions. High quality "third party" re-implementations of published models are also relevant, especially those involving models that are of wide interest. ... [Information of the supplier]
One of the main objectives of the HBP is to create and operate six Information and Communications Technology (ICT) Platforms, which are the core of the emerging HBP research infrastructure for brain research. Starting 30 March 2016, the scientific community worldwide can begin exploring the initial versions of the six HBP ICT Platforms. The Platforms embody the key objectives of the HBP, to gather and disseminate data describing the brain, to simulate and build models of the brain, to develop brain-inspired computing and robotics, and to create a global scientific community around the developing research infrastructure. The Platforms consist of prototype hardware, software tools, databases, programming interfaces, and initial data-sets, which will be refined and expanded on an on-going basis in close collaboration with end-users. The development of the Platforms has been the result of an extensive multidisciplinary effort involving more than 750 scientific collaborators and engineers from 114 institutions in 24 countries. The Platforms are as follows: the Neuroinformatics Platform, the Brain Simulation Platform, the High Performance Analytics and Computing Platform, the Medical Informatics Platform, the Neuromorphic Computing Platform and the Neurorobotics Platform. ... [Information of the supplier, modified]