One of the main objectives of the HBP is to create and operate six Information and Communications Technology (ICT) Platforms, which are the core of the emerging HBP research infrastructure for brain research. Starting 30 March 2016, the scientific community worldwide can begin exploring the initial versions of the six HBP ICT Platforms. The Platforms embody the key objectives of the HBP, to gather and disseminate data describing the brain, to simulate and build models of the brain, to develop brain-inspired computing and robotics, and to create a global scientific community around the developing research infrastructure. The Platforms consist of prototype hardware, software tools, databases, programming interfaces, and initial data-sets, which will be refined and expanded on an on-going basis in close collaboration with end-users. The development of the Platforms has been the result of an extensive multidisciplinary effort involving more than 750 scientific collaborators and engineers from 114 institutions in 24 countries. The Platforms are as follows: the Neuroinformatics Platform, the Brain Simulation Platform, the High Performance Analytics and Computing Platform, the Medical Informatics Platform, the Neuromorphic Computing Platform and the Neurorobotics Platform. ... [Information of the supplier, modified]
NRCAM, the National Resource for Cell Analysis and Modeling is developing a unique software modeling environment, the Virtual Cell, for quantitative cell biological research. Approaches in computational cell biology are coupled with high resolution light microscopy to facilitate the interplay between experimental manipulation and computational simulation of specific cellular functions that can range from simple molecular motors to tissue-wide process. The Virtual Cell is deployed as a distributed application that is used over the Internet. It is freely accessible to all members of the scientific community. The Virtual Cell has been specifically designed to be a tool for a wide range of scientists, from experimental cell biologists to theoretical biophysicists. Likewise the creation of models can range from the simple, to evaluate hypotheses or to interpret experimental data, to complex multi-layered models used to probe the predicted behavior of complex, highly non-linear systems. Such models can be based on both experimental data and purely theoretical assumptions. ... [Information of the supplier]
Genes to Cognition (G2C) is a neuroscience research programme with the dual aim of discovering fundamental biological principles and important insights into brain disease. G2C is an international collaborative program initiated by Dr. Seth Grant and supported by the Wellcome Trust following the discovery that multiprotein complexes formed by intracellular proteins and neurotransmitter receptors were important for neuronal plasticity and behaviour. Multiprotein complexes are involved with dozens of brain diseases, control multiple types of behaviours and are involved with the responses to drug treatments of mental disorders. Evolutionary studies show ancient forms of the complexes evolved over a billion years in single cell animals and may represent the origin of the brain. The long term goal is to understand the molecular basis of the extraordinarily complex brain of humans, how this complexity evolved, what it confers on behaviour and why brain evolution made us susceptible to mental illness. The G2C project has a unique database called G2Cdb that houses data resources from the research program and G2C has a very interesting educational program called G2COnline. ... [Information of the supplier, modified]
The Science Environment for Ecological Knowledge (SEEK) is a five year initiative designed to create cyberinfrastructure for ecological, environmental, and biodiversity research and to educate the ecological community about ecoinformatics. SEEK participants are building an integrated data grid (EcoGrid) for accessing a wide variety of ecological and biodiversity data and analytical tools (Kepler) for efficiently utilizing these data stores to advance ecological and biodiversity science. An intelligent middleware system (SMS) will facilitate integration and synthesis of data and models within these systems. The three components of the SEEK cyberinfrasture are: (1) the EcoGrid, (2) a Semantic Mediation system, and (3) an Analysis and Modeling system. These infrastructure components will be built with input and participation from three SEEK working groups: (1) Knowledge Representation, (2) Biological Taxonomy and Classification, and (3) Biodiversity and Ecological Analysis and Modeling. ... [Information of the supplier]
Our goal: to understand protein folding, misfolding, and related diseases. Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery. Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes. You can help by simply running a piece of software. Folding@home is a distributed computing project -- people from throughout the world download and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved. We have had several successes. You can read about them on our Science page, on our Awards page, or go directly to our Results page. ... [Information of the supplier, modified]
BioCatalogue will provide a curated and comprehensive catalogue of biological web services, thereby enabling users (people and programs) to discover and use these services easily. It also aims to provide a platform with several (standardized) interfaces and a suite of tools for registration of services by the community of users as well as empower the community to extend and enhance the system. BioCatalogue will provide a centralized biological web services market place which will be accessible to the world as it will be searchable and indexable to search engines. BioCatalogue will provide a quality of service standard for biological web services thereby enabling services to be classified and checked for availability, reliability and other quality measures. BioCatalogue is a BBSRC funded project and has been running since 1st June 2008. The project is a joint venture between the EMBL-EBI (led by Rodrigo Lopez) and the myGrid project at the University of Manchester (led by Carole Goble). ... [Information of the supplier]
ViBRANT is a European Union FP7 funded project starting in December 2010 that will support the development of virtual research communities involved in biodiversity science. Our goal is to provide a more integrated and effective framework for those managing biodiversity data on the Web. ViBRANT provides: (1) A virtual research environment (Scratchpads) where users can safely store, share and manage their research information; (2) Analytical services for users to build identification keys and phylogenetic trees; (3) A publication platform for users to automatically compile biodiversity science manuscripts from their research database; (4) A portal for users to centrally access publicly accessible biodiversity research information and literature; (5) Training, helping research communities to use these tools and services; (6) A standards compliant technical architecture that can be sustained by biodiversity research community. ... [Information of the supplier]
GenMAPP is a free computer application designed to visualize gene expression and other genomic data on maps representing biological pathways and groupings of genes. Integrated with GenMAPP are programs to perform a global analysis of gene expression or genomic data in the context of hundreds of pathway MAPPs and thousands of Gene Ontology Terms (MAPPFinder), import lists of genes/proteins to build new MAPPs (MAPPBuilder), and export archives of MAPPs and expression/genomic data to the web. The main features underlying GenMAPP are: 1) Draw pathways with easy to use graphics tools; 2) Color genes on MAPP files based on user-imported genomic data; 3) Query data against MAPPs and the GeneOntology. ... [Information of the supplier]
The goal of this joint project between the Swiss-Prot group of the Swiss Institute of Bioinformatics and the Medical Informatics Service of the University Hospital of Geneva is to explore the development of question-answering systems in functional genomics. [Information of the supplier]
PlutoF provides cloud database and computing services for the taxonomical, ecological, phylogenetical, etc. research. The purpose of the platform is to provide synergy through common modules for the classifications, taxon names, analytical tools, etc. It allows to address integrated questions in ecology and coevolution of taxa. Different types of the species occurrences, viz. preserved specimens, DNA sequences, human observations, references can be stored in PlutoF as well. PlutoF has no restrictions on taxon and geographic coverage and therefore can be used for the databasing interacting taxa. It includes also collection management module. ... [Information of the supplier]