On behalf of the Japanese Society of Developmental Biologists (JSDB) and the Gesellschaft für Entwicklungsbiologie (GfE) we cordially invite you to attend the Joint Meeting of the German and Japanese Societies of Developmental Biologists (GfE/JSDB Meeting 2017) to be held in Kiel, Germany from 15–18 March 2017. In a joint effort, we've put together a program we believe will be stimulating and representing current trends and excitements in Developmental Biology with specific focus on research carried out in Japan and Germany. Through a variety of inspiring invited keynote lectures, talks from the participants, workshops and poster sessions, we will discuss the major breakthroughs and developments in Developmental Biology. The emphasis of the meeting is very much upon discussion and there is plenty of time within the program to make this possible. In addition to an excellent scientific program, there will be many opportunities for networking as well as enjoyable social events. In a special ceremony held at Kiel City Hall, the Klaus Sander Prize as well as the Hilde Mangold Prize of the GfE will be awarded. We are also celebrating 50 years of JSDB. A Young Investigator Lunch "Career perspectives in Developmental Biology" sponsored by the DFG and the Alexander von Humboldt Foundation will not only inform the junior scientist about funding possibilities but also allow one-to-one talks with representatives of the DFG, the JSPS, the Alexander von Humboldt Foundation and members of the corresponding reviewing panels. If you would like to join the conference and present your observations in a talk or a poster, please register via www.gfe-meeting.de. Should you have any questions please contact us or the scientific management of this meeting, Mrs. Wenke Schütte/Conventus at any time. We hope you find the agenda interesting and join us in Kiel, the capital of the northern German federal state of Schleswig-Holstein with its beautiful setting on the Kiel Fjord. ... [Information of the supplier]
This symposium focuses on the role of metabolism in controlling cellular and developmental programs in its spatial and temporal complexity. There is a fundamental interest in deciphering the intricate link between metabolism and regulatory cellular programs during cell differentiation and the development of multicellular organisms. Recent technological progress has enabled us to analyse metabolism and metabolic activities with spatio-temporal resolution. This creates unprecedented potential to address how metabolic state impacts on cellular and developmental programs. Aims: It is the overarching goal of this meeting to enable interdisciplinary discussion on the role of metabolism in controlling cellular and developmental programs in its spatial and temporal complexity. Special focus will be given to discuss emerging imaging or biosensor technologies and bioinformatics and how they can enable addressing fundamental biological questions. ... [Information of the supplier]
The p53 tumor suppressor gene was initially identified as being essential for the DNA damage checkpoint, but it was subsequently found to have a broader function after cellular stress, such as oncogene activation or hypoxia. The p53 protein functions as a tetrameric transcription factor found at very low levels in normal unstressed cells. After stress, different pathways lead to post-translational modification of the protein and its stabilization. p53 database contains 16,000+ entries corresponding to TP53 mutations found in tumors, normal skin, and noncancerous diseases such as rheumatoid arthritis. The database also includes germline mutations found in Li-Fraumeni syndrome (LFS) and LFS-like syndrome. ... [Information of the supplier, modified]
SWISS-2DPAGE is an annotated two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) and SDS-PAGE database established in 1993 and maintained collaboratively by the Biomedical Proteomics Reasearch Group (BPRG) of the Geneva University and the Proteome Informatics Group of the Swiss Institute of Bioinformatics (SIB). The SWISS-2DPAGE database assembles data on proteins identified on various 2-D PAGE and SDS-PAGE maps. Each SWISS-2DPAGE entry contains textual data on one protein, including mapping procedures, physiological and pathological information, experimental data (isoelectric point, molecular weight, amino acid composition, peptide masses) and bibliographical references. In addition to this textual data, SWISS-2DPAGE provides several 2-D PAGE and SDS-PAGE images showing the experimentally determined location of the protein, as well as a theoretical region computed from the sequence protein, indicating where the protein might be found in the gel. Cross-references are provided to Medline and other federated databases. ... [Information of the supplier]
AACompIdent is a tool which allows the identification of a protein from its amino acid composition. It searches the Swiss-Prot and / or TrEMBL databases for proteins, whose amino acid compositions are closest to the amino acid composition given. [Information of the supplier]
This page allows you to test an antibody sequence against the Kabat sequence database. Any unusual residues (occurring in < 1% of chains in the database) will be reported to you. This allows the identification of potential cloning artifacts and sequencing errors. The current Kabat database contains 6014 light chains and 7895 heavy chains. ... [Information of the supplier]
CATH is a hierarchical classification of protein domain structures, which clusters proteins at four major levels, Class(C), Architecture(A), Topology(T) and Homologous superfamily (H).Class, derived from secondary structure content, is assigned for more than 90% of protein structures automatically. Architecture, which describes the gross orientation of secondary structures, independent of connectivities, is currently assigned manually. The topology level clusters structures into fold groups according to their topological connections and numbers of secondary structures. The homologous superfamilies cluster proteins with highly similar structures and functions. The assignments of structures to fold groups and homologous superfamilies are made by sequence and structure comparisons. The boundaries and assignments for each protein domain are determined using a combination of automated and manual procedures. These include computational techniques, empirical and statistical evidence, literature review and expert analysis. ... [Information of the supplier]
MOLMOL is a molecular graphics program for displaying, analyzing, and manipulating the three-dimensional structure of biological macromolecules, with special emphasis on the study of protein or DNA structures determined by NMR. The program runs on UNIX and Windows NT/95/98/2000 and is freely available. [Information of the supplier]
BioMagResBank (BMRB) is the publicly-accessible depository for NMR results from peptides, proteins, and nucleic acids recognized by the International Society of Magnetic Resonance and by the IUPAC-IUBMB-IUPAB Inter-Union Task Group on the Standardization of Data Bases of Protein and Nucleic Acid Structures Determined by NMR Spectroscopy. In addition, BMRB provides reference information and maintains a collection of NMR pulse sequences and computer software for biomolecular NMR. Access to data in BMRB is free directly from its web site (URL http://www.bmrb.wisc.edu) and ftp site (ftp.bmrb.wisc.edu) and will remain so as public funding permits. The concept of a biomolecular NMR data bank was developed under a five-year research grant awarded to the University of Wisconsin-Madison from the National Library of Medicine, National Institutes of Health. ... [Information of the supplier]