Bgee is a database to retrieve and compare gene expression patterns between animal species. Bgee first maps heterogeneous expression data (currently EST, Affymetrix, and in situ hybridization data) on anatomy and development of different species. Then, in order to perform automated cross species comparisons, homology relationships across anatomies, and comparison criteria between developmental stages, are designed. Data can be retrieved by ontology browsing, textual search, expression search, or advanced expression search. Gene expression patterns can be compared by selecting any gene family (e.g. ENSFM00500000270089). The full content of the Bgee expression database, the ontologies, the homology links between anatomical ontologies, and the relationships between developmental ontologies, are all available in the download section. More information is provided in the documentation. All data sources used in Bgee are listed on the data sources page. ... [Information of the supplier]
The Barcoding Fauna Bavarica project is an All Species DNA barcoding campaign of the Zoologische Staatssammlung in Munich (ZSM) and the Canadian Centre for DNA Barcoding (CCDB). It represents a major component of Germany's contribution to the International Barcode of Life Project. Core funding comes from the Bavarian State Ministry of Science, Research, and the Arts, and from Genome Canada through the Ontario Genomics Institute. (Stefan Schmidt, unter https://www.youtube.com/watch?v=KOQEYZRrB-s). ... [Miscellaneous as indicated]
WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible information concerning the genetics, genomics and biology of C. elegans and some related nematodes. [Information of the supplier]
The cyclic AMP response element (CRE)-binding protein (CREB) family of activators (CREB1, CREM, ATF1) functions in diverse physiological processes, including the control of cellular metabolism, growth-factor-dependent cell survival, and developement an plasticity of neurons. A diverse range of signals, including cAMP, calcium, stress and mitogenic stimuli, can activate CREB and promote target gene expression. This database is dedicated to catogerize CREB target genes in a comprehensive and easy-to-search way. We have used a multi-layered approach to predict, validate and chracterize CREB target genes. For each gene, we try to provide the following information: 1. CREB binding sites on the promoters, 2. Promoter occupancy by CREB, 3. Gene activation by cAMP in tissues. The data are for humans, rats, and mice. ... [Information of the supplier, modified]
The Genetic Association Database is an archive of human genetic association studies of complex diseases and disorders. The goal of this database is to allow the user to rapidly identify medically relevant polymorphism from the large volume of polymorphism and mutational data, in the context of standardized nomenclature. ... [Information of the supplier]
T1DBase is a public website and database that supports the type 1 diabetes (T1D) research community. It is being created by a joint effort between the Institute for Systems Biology, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory and the Juvenile Diabetes Research Foundation International. T1DBase collects information from public sources and from collaborating laboatories, integrates this information, and presents it in a form that is useful for T1D researchers. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; microarray data; functional annotation of genes active in beta cells; and "global"datasets, generally from the literature, that are useful for systems biology studies. ... [Information of the supplier, modified]
The Interactive Fly - a cyberspace guide to Drosophila development and metazoan evolution - was first released July/August 1996, with updates provided at approximately one month intervals, through September 1997 (edition 13). Updating quarterly started with edition 14. With edition 40, the Interactive Fly began to schedule updates three times a year: fall, winter and spring. ... [Information of the supplier, modified]
FlyView is an image database on Drosophila development and genetics, especially on expression patterns of genes (enhancer trap lines, cloned genes). Our aim is to establish the possibility to compare images on the computer screen and to search for special patterns at different developmental stages. FlyView presents three possibilities for searching: Search for pattern elements (with keywords in text descriptions, getting back images with links to the appropriate stocks), search for stocks (with stock number, allele, genotype, chromosome, insertion site, viability, developmental stage or expression pattern, getting back a list of found stocks that guide to full descriptions (including links to images, e-mail address for ordering and, in the case of BDGP lines, also direct links to FlyBase and/or EofD)) and Overview (an actual list of all lines included in FlyView, linked to stock descriptions and images). The success of this database exclusively depends on the activity of the Drosophila community. All Drosophila workers are asked to contribute to this database by submitting images and accompanying text. ... [Information of the supplier, modified]
This database presents the current results of large scale protein trapping screens that provide both information on which cells express each tagged gene, and subcellular localization of GFP-tagged proteins. It contains sequence coordinates of inserted transposons, information on the tagged genes, and images with expression patterns of GFP in Drosophila tissues. FlyTrap serves as the data repository for lines generated in the Chia, Cooley, and Spradling labs. The protein trap stocks listed in FlyTrap are available for distribution. ... [Information of the supplier, modified]
The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community. ... [Information of the supplier]