One of the main objectives of the HBP is to create and operate six Information and Communications Technology (ICT) Platforms, which are the core of the emerging HBP research infrastructure for brain research. Starting 30 March 2016, the scientific community worldwide can begin exploring the initial versions of the six HBP ICT Platforms. The Platforms embody the key objectives of the HBP, to gather and disseminate data describing the brain, to simulate and build models of the brain, to develop brain-inspired computing and robotics, and to create a global scientific community around the developing research infrastructure. The Platforms consist of prototype hardware, software tools, databases, programming interfaces, and initial data-sets, which will be refined and expanded on an on-going basis in close collaboration with end-users. The development of the Platforms has been the result of an extensive multidisciplinary effort involving more than 750 scientific collaborators and engineers from 114 institutions in 24 countries. The Platforms are as follows: the Neuroinformatics Platform, the Brain Simulation Platform, the High Performance Analytics and Computing Platform, the Medical Informatics Platform, the Neuromorphic Computing Platform and the Neurorobotics Platform. ... [Information of the supplier, modified]
Grid computing is regarded as one of the critical success factors in biomedical Research. The joint project MediGRID unifies well known research institutes in the area of medicine, biomedical informatics and life sciences into a consortium. Numerous associated partners from industry, healthcare and research facilities ensure a broad representation of these communities. The main goal of MediGRID is the Development of a Grid middleware integration platform enabling eScience services for biomedical life science. Therefore the consortium allocated the tasks in different modules. The four methodological modules (middleware, ontology, resource fusion and eScience) plan to incrementally develop and provide a Grid infrastructure while taking into account the need of the biomedical users. The user communities are represented in three research modules for biomedical informatics, image processing and clinical research. ... [Information of the supplier]
An international research consortium has been formed to create the most detailed and medically useful picture to date of human genetic variation. The 1000 Genomes Project will involve sequencing the genomes of at least a thousand people from around the world. The project will receive major support from the Wellcome Trust Sanger Institute in Hinxton, England, the Beijing Genomics Institute Shenzhen in China and the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH). Drawing on the expertise of multidisciplinary research teams, the 1000 Genomes Project will develop a new map of the human genome that will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. As with other major human genome reference projects, data from the 1000 Genomes Project will be made swiftly available to the worldwide scientific community through freely accessible public databases. ... [Information of the supplier]
The NCI's Cancer Genome Anatomy Project sought to determine the gene expression profiles of normal, precancer, and cancer cells, leading eventually to improved detection, diagnosis, and treatment for the patient. Resources generated by the CGAP initiative are available to the broad cancer community. Interconnected modules provide access to all CGAP data, bioinformatic analysis tools, and biological resources allowing the user to find "in silico" answers to biological questions in a fraction of the time it once took in the laboratory. ... [Information of the supplier]
In September, 2001, the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) convened a working group of its National Advisory Council to develop a strategic plan for Stem Cells and Developmental Biology. The working group made several recommendations, with the overall goals of providing new strategies for repairing or replacing damaged organs and generating new insights into pathologic processes underlying developmental defects and disease. There is the need for a more thorough understanding of organogenesis so that tissue degeneration and congenital malformations might be prevented and treated. The goal of GUDMAP is a fundamental description of the developing kidney and GU tract. The panel recommended that the following three objectives be combined to form the GUDMAP. a) High throughput in situ hybridization analyses to define the expression pattern of genes expressed in the developing kidney and GU tract, b) High resolution gene expression analyses to define gene expression during developmental time, the overlap in gene expression patterns, and the correlation between boundaries of gene expression and boundaries of anatomic or functional domains and c) Development of a database to house and annotate the above data and to provide rapid access of this data to the entire research community. Microarray analyses and the generation of murine strains with genetic markers are also goals of GUDMAP which serve to bolster the overall aim of defining molecular and cellular anatomy through developmental time. ... [Information of the supplier, modified]
COST is an intergovernmental framework for European Cooperation in Science and Technology, allowing the coordination of nationally-funded research on a European level. COST fosters the establishment of scientific excellence in the nine key domains. The domain "Biomedicine and Molecular Biosciences" (BMBS) covers all areas of medicine as practiced in Europe and basic, preclinical and clinical medical research developed to materialise the “bench to bedside” concept. ... [Information of the supplier, modified]
The Science Environment for Ecological Knowledge (SEEK) is a five year initiative designed to create cyberinfrastructure for ecological, environmental, and biodiversity research and to educate the ecological community about ecoinformatics. SEEK participants are building an integrated data grid (EcoGrid) for accessing a wide variety of ecological and biodiversity data and analytical tools (Kepler) for efficiently utilizing these data stores to advance ecological and biodiversity science. An intelligent middleware system (SMS) will facilitate integration and synthesis of data and models within these systems. The three components of the SEEK cyberinfrasture are: (1) the EcoGrid, (2) a Semantic Mediation system, and (3) an Analysis and Modeling system. These infrastructure components will be built with input and participation from three SEEK working groups: (1) Knowledge Representation, (2) Biological Taxonomy and Classification, and (3) Biodiversity and Ecological Analysis and Modeling. ... [Information of the supplier]
Our goal: to understand protein folding, misfolding, and related diseases. Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery. Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes. You can help by simply running a piece of software. Folding@home is a distributed computing project -- people from throughout the world download and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved. We have had several successes. You can read about them on our Science page, on our Awards page, or go directly to our Results page. ... [Information of the supplier, modified]
BioCatalogue will provide a curated and comprehensive catalogue of biological web services, thereby enabling users (people and programs) to discover and use these services easily. It also aims to provide a platform with several (standardized) interfaces and a suite of tools for registration of services by the community of users as well as empower the community to extend and enhance the system. BioCatalogue will provide a centralized biological web services market place which will be accessible to the world as it will be searchable and indexable to search engines. BioCatalogue will provide a quality of service standard for biological web services thereby enabling services to be classified and checked for availability, reliability and other quality measures. BioCatalogue is a BBSRC funded project and has been running since 1st June 2008. The project is a joint venture between the EMBL-EBI (led by Rodrigo Lopez) and the myGrid project at the University of Manchester (led by Carole Goble). ... [Information of the supplier]
ViBRANT is a European Union FP7 funded project starting in December 2010 that will support the development of virtual research communities involved in biodiversity science. Our goal is to provide a more integrated and effective framework for those managing biodiversity data on the Web. ViBRANT provides: (1) A virtual research environment (Scratchpads) where users can safely store, share and manage their research information; (2) Analytical services for users to build identification keys and phylogenetic trees; (3) A publication platform for users to automatically compile biodiversity science manuscripts from their research database; (4) A portal for users to centrally access publicly accessible biodiversity research information and literature; (5) Training, helping research communities to use these tools and services; (6) A standards compliant technical architecture that can be sustained by biodiversity research community. ... [Information of the supplier]
