H-DBAS is a unique database of alternative splicing (AS) based on H-InvDB. The features of H-DBAS is as follows: 1) Representative AS variants (RASVs) were identified from 8 data sets consist of 6 mammalian model organisms (human, mouse, rat, chimpanzee, macaque and dog). The contents of data sets and the corresponding species are as follows: Full-length cDNA data set, mRNA data set, RNA data set 2) Equally-spliced variants (ESVs) were identified from RASVs between human and mouse, rat, chimpanzee, macaque and dog by using comparative genomics. Splice sites and splice motifs affecting SNPs can be observed in human. 3) RASVs affecting protein functions (protein motif, GO, subcellular localization signal and transmembrane domain) can be observed in human. 4) AS junctions expressed in specified cellular fractions (cytoplasm, nuclear and polysome) of human cell were detected by using RNA-Seq tags. The translation validation of the variants having AS junctions were analyzed by compared with RefSeq junctions. The results are shown from RNA-Seq analysis page. ... [Information of the supplier]
DDBJ (DNA Data Bank of Japan) began DNA data bank activities in earnest in 1986 at the National Institute of Genetics (NIG). From the beginning, DDBJ has been functioning as one of the International DNA Databases, including EBI in Europe and NCBI in the USA as the two other members. Consequently, we have been collaborating with the two data banks through exchanging data and information on Internet and by regularly holding two meetings, the International DNA Data Banks Advisory Meeting and the International DNA Data Banks Collaborative Meeting. DDBJ is the sole DNA data bank in Japan, which is officially certified to collect DNA sequences from researchers and to issue the internationally recognized accession number to data submitters. We collect data mainly from Japanese researchers, but of course accept data and issue the accession number to researchers in any other countries. Since we exchange the collected data with EMBL/EBI and GenBank/NCBI on a daily basis, the three data banks share virtually the same data at any given time. We also provide worldwide many tools for data retrieval and analysis developed by at DDBJ and others. ... [Information of the supplier]