We present a neural network based method (ChloroP) for identifying chloroplast transit peptides and their cleavage sites. Using cross-validation, 88% of the sequences in our homology reduced training set were correctly classified as transit peptides or nontransit peptides. This performance level is well above that of the so far only publicly available chloroplast localization predictor PSORT. Cleavage sites are predicted using a scoring matrix derived by an automatic motif-finding algorithm. Approximately 60% of the known cleavage sites in our sequence collection were predicted to within +- 2 residues from the cleavage sites given in SWISS-PROT. An analysis of 715 A. thaliana sequences from SWISS-PROT suggests that the ChloroP method should be useful for the identification of putative transit peptides in genome-wide sequence data. ... [Information of the supplier]
Gegründet 1975 unter dem Namen "Deutsche Gesellschaft für Zellbiologie e.V.". Die Zahl ihrer Mitglieder beträgt heute 1100. Das zentrale Anliegen der Zellbiologie ist die Erforschung der Lebensvorgänge und deren molekulare Regulation in der Zelle. Sowohl methodisch als auch in den experimentellen Modellen ist die Zellbiologie mehr und mehr zu einer integrativen Wissenschaft geworden. Es gibt vielfältige Überschneidungen mit Fragestellungen der Biochemie, Biophysik, Entwicklungsbiologie, Genetik, Immunologie, Mikrobiologie, Parasitologie und der medizinischen Grundlagenforschung. Auf diese Weise wurde ein umfangreiches Fachwissen von Experten vieler Fachgebiete in der Gesellschaft zusammengeführt. Die von den Zellbiologen erarbeiteten Grundlagen wirken zunehmend auf die biomedizinische Forschung ein und führten in einzelnen Fällen bereits zu einem besseren Verständnis von Krankheiten auf molekularer Ebene. Die Deutsche Gesellschaft für Zellbiologie veranstaltet eine Jahrestagung, die jedes Jahr im März in einer anderen Stadt abgehalten wird. 3mal jährlich erhält jedes Mitglied die "DGZ-Mitteilung". Die DGZ verleiht verschiedene Preise für Doktor- und Forschungsarbeiten. [vdbiol] ... [Sonstige Quelle laut Angabe]
The IFCB has its historical roots in the early 1930's. It was formally established in St. Louis in 1972 to coordinate and support Cell Biology activities throughout the world, as well as representing cell biology in the International Union of Biological Sciences. The affiliation makes the IFCB a constituent of the International Council of Scientific Unions (ICSU), and puts our congresses officially under the aegis of the latter. This is of particular importance to colleagues in some countries who may become eligible for grants to attend international congresses sponsored by the ISCU. The IFCB is also represented in the International Cell Research Organization (ICRO) which functions in UNESCO. The IFCB continues to fulfill its functions with a minimum of organization and at a low overhead cost. The organization of each international congress is delegated to a sponsoring member society which takes full responsibility as host for the congress. The IFCB normally provides a block grant to the congress organizers to help young cell biologists mainly from developing countries to attend the meetings. These funds are allocated by the appropriate committee of the congress (which includes an appropriate IFCB official or nominee) and is based on an assessment of the scientific quality of the abstracts submitted. Grants usually cover only part of the travel costs or subsistence. ... [Information of the supplier]
