Understanding both the climate and the functioning of the earth as a system is one of the largest challenges of our time. In this context, polar regions play a pivotal role. Melting ice caps at the poles will cause sea levels to rise and, consequently, will make many coastal areas uninhabitable. Thawing of permafrost regions will release enormous quantities of the greenhouse gas methane. Hence, what happens to the polar regions has a direct effect on our lives. In the past, three large-scale international initiatives were aimed at studying the polar regions. These extensive scientific events, with numerous expeditions, establishment of new research stations and internationally coordinated observation programmes, significantly enhanced our knowledge of the polar regions. The International Polar Year 2007/08 intends to continue this tradition. Large-scale measuring campaigns and field studies will facilitate our understanding of the earth and its climate. This will be the only way to prepare for upcoming changes of our environment. ... [Information of the supplier, modified]
The MicrobesOnline genome database contains over 300 prokaryotic genomes. All genomes are automatically analyzed through the VIMSS genome pipeline. We use publicly available sequence analysis tools and databases to search for homologs (NCBI BLAST, SwissProt, COG) and protein domains (InterPro), to assign gene ontologies (Gene Ontology Consortium) and EC numbers and to map the metabolic pathways (KEGG). We then link the orthology relationships between genes, predict operon structures and regulon networks. Most of the genomes are downloaded from NCBI and genes are parsed from GenBank files. When an incomplete genome is directly downloaded from a sequencing center, we predict protein coding genes using CRITICA and Glimmer, tRNA genes using tRNAscan and other RNA genes by BLASTn. All of the info in the VIMSS genome database is freely available on our website. ... [Information of the supplier]
MLER aims to provide a contemporary and expanding resource of expert information about the ecology, diversity and evolution of micro-organisms for students, K-12 teachers, university faculty, as well as for the general public. The resources of MLER include materials that can be accessed through the internet and cover microbial ecology, their evolution and diversity. These resources are built around themes. The initial themes will be directed to microbial life in extreme environments and microbial life in oceans. With close ties to the research community, MLER shortens the distance between researchers and students. Our coverage emphasizes the world of microbial organisms - the eubacteria (= bacteria), archaebacteria (= archaea), viruses, and the protists (protozoa, algae, slime molds). ... [Information of the supplier]
The Fungal Genetics Stock Center is a resource available to the Fungal Genetics research community and to educational and research organizations in general. The FGSC was founded following recommendations of the Genetics Society of America in 1960 at Dartmouth College. In 1960 there were approximately 400 strains at the FGSC. Now there are over 8,000 Neurospora strains, a growing number of Neurospora knock-outs, over 2,000 Aspergillus strains and various representatives of other fungi. Additionally, the FGSC has cloned genes, and gene libraries. In early 2001, we added strains of Magnaporthe grisea and molecular tools for working with them. In 2003 and 2004, we accepted nearly 50,000 Magnaporthe knock out mutants. ... [Information of the supplier, modified]
The Achaeal Genome Browsers at UCSC were developed by members of the Lowe Lab, with significant support from the UCSC Human Genome Browser group. The Archaeal Browsers are run by a slightly modified version of the UCSC Human Genome Browser system. Additional extremophile and other model bacteria are available from main genome menu. New species are added as they become public, and upon request. Get Started Browsing: click on a species in the archaeal phylogenetic tree, or select a species from genome table below, or go directly to the genome menu. ... [Information of the supplier, modified]
In the 21st century, it is becoming increasingly important for students to be aware of and understand basic biotechnological and microbiological concepts. As always, these scientific concepts are most effectively conveyed through hands-on laboratory experiences. However, laboratory exercises are challenging because of the potential risk of student exposure to harmful microbes and chemicals, challenges in maintaining sterility of cultures, cost of scientific materials, and length of time required for preparation and laboratory experiments. Because of the urgent need to improve and expand the biotechnology and microbiology component of curricula using novel, safe, and effective approaches, we have developed this web site. As the centerpiece of this project, we have utilized the halophilic microbe, Halobacterium species NRC-1, which has been extensively studied in our laboratory for the last 20 years, as an ideal teaching vehicle. ... [Information of the supplier]
Aspergillus flavus is a plant, animal, and human pathogen that produces the carcinogen, aflatoxin. An organized multidisciplinary team is coordinating research efforts to control this fungus and to prevent the formation of its toxin in food and feeds. [Information of the supplier]
PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes. Each entry in PHI-base is curated by domain experts and is supported by strong experimental evidence (gene disruption experiments, STM etc), as well as literature references in which the original experiments are described. Each gene in PHI-base is presented with its nucleotide and deduced amino acid sequence, as well as a detailed description of the predicted protein's function during the host infection process. To facilitate data interoperability, we have annotated genes using controlled vocabularies and links to external sources. ... [Information of the supplier]
Funded as part of the Wellcome Trust Functional Genomics Development Initiative, the GeneDB project is aiming to develop and maintain curated database resources for three organisms: Schizosaccharomyces pombe, which has been completely sequenced, and the kinetoplastid protozoa Leishmania major and Trypanosoma brucei, whose genome sequences have yet to be completed. The goals are to capture, store and manage data for integration with emerging functional genomics and proteomics projects and to provide an easy-to-use, user-friendly interface, including a variety of graphical displays. It is envisaged that the generic database structure will subsequently be adopted to integrate datasets for other organisms, both prokaryotic and eukaryotic, that have been sequenced by the Sanger Institute Pathogen Sequencing Unit. To this extend, datasets for Saccharomyces cerevisiae as well as the filamentous fungus Aspergillus fumigatus are already available through GeneDB. The database has been developed through close collaboration between Sanger Institute software developers, on-site organism specific curators and representatives of the research communities. The data within geneDB are manually annotated and curated, frequently updated and, because of the structured annotation and use of controlled vocabulary, easy to precisely query. The database is under constant review and new functionality will be added as it evolves. ... [Information of the supplier]
Die Webseite stellt als Online-Lehrbuch das begleitende Angebot zu dem Buch "Through the microscope" von Timothy Paustian und Gary Roberts da. Es behandelt alle Aspekte der Mikrobiologie in 26 verschiedenen Kapiteln. Frei verfügbar sind zunächst nur die Kapitel 1,2 und 15 - nach Registrierung ist jedoch das komplette Angebot zugänglich. ... [Redaktion vifabio]
