The European Molecular Biology Laboratory is a non-profit organisation and a basic research institute funded by public research monies from 18 member states. Research at EMBL is conducted by approximately 80 independent groups covering the spectrum of molecular biology. The cornerstones of EMBL's mission are: to perform basic research in molecular biology, to train scientists, students and visitors at all levels, to offer vital services to scientists in the member states, and to develop new instruments and methods in the life sciences, and technology transfer. ... [Information of the supplier]
The BioCurrents Research Center (BRC) specializes in the development and utilization of a range of technologies to examine the chemical profiles of the living cell, specifically within the complex and dynamic boundary layer. The technologies are employed by in-house researchers and collaborators from around the world to address a range of human health issues including diabetes, infertility and degenerative diseases. ... [Information of the supplier]
GOBASE is a taxonomically broad organelle genome database that organizes and integrates diverse data related to mitochondria and chloroplasts. In its next phase, GOBASE will also include information on representative bacteria that are thought to be specifically related to the bacterial ancestors of mitochondria and chloroplasts ... [Information of the supplier]
The membrane organization and subcellular location of a protein can provide information about its functional role. Historically, these data have been difficult to produce on a large scale for higher eukaryotic organisms. However, recent advances in membrane organization prediction methods and high-throughput subcellular localization assays have made it possible to generate these datasets. LOCATE is a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing over 1700 peer-reviewed publications. The results of the MemO pipeline and the subcellular localization methods are stored in the database with supporting information including a graphical depiction of the membrane organization juxtaposed with InterPro-predicted features and links to several external databases. The database is searchable by subcellular location, protein class, descriptive keyword, and sequence similarity. The data are retrievable in human- and machine-readable formats and in batch. ... [Information of the supplier]
The Membrane Protein Data Bank (MPDB) is an online, searchable, relational database of structural and functional information on integral, anchored and peripheral membrane proteins and peptides. Data originates from the Protein Data Bank and other databases, and from the literature. Structures are based on X-ray and electron diffraction, nuclear magnetic resonance and cryoelectron microscopy. The MPDB is searchable online by protein characteristic, structure determination method, crystallization technique, detergent, temperature, pH, author, etc. Record entries are hyperlinked to the PDB and Pfam for viewing sequence, three-dimensional structure and domain architecture, and for downloading coordinates. Links to PubMed are also provided. ... [Information of the supplier]
MPtopo is a curated database of membrane proteins with experimentally validated transmembrane (TM) segments. The database is maintained in SQL form using the MySQL server. It can be searched using MPtopoQuerier, a java applet developed for this purpose. Retrieved sequences can be examined automatically by MPEx, a java-based hydropathy-plot tool. MPtopo currently contains a total of 167 proteins with 1028 TM segments. ... [Information of the supplier, modified]
The DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures) is the most comprehensive Biological Resource Centre in Europe. With more than 14 000 microorganisms, 900 plant viruses, 550 human and animal cell lines, 500 plant cell cultures and more than 6 300 cultures deposited for the purposes of patenting, we have demonstrated our obligation to serve science for decades. The DSMZ is an independent, non-profit organisation. ... [Information of the supplier]
The Cell: An Image Library™ is a freely accessible, easy-to-search, public repository of vetted and annotated images, videos, and animations of cells from a variety of organisms, showcasing cell architecture, intracellular functionalities, and both normal and abnormal processes. The purpose of this database is to advance research, education, and training, with the ultimate goal of improving human health. ... [Information of the supplier]
TCDB is a curated database of factual information from over 10,000 published references. The database contains about 3,000 protein sequences. The database details a comprehensive IUBMB approved classification system for membrane transport proteins known as the Transporter Classification (TC) system. The TC system is analogous to the Enzyme Commission (EC) system for classification of enzymes, but incorporates phylogenetic information additionally. TCDB is operated by the Saier Lab Bioinformatics Group. ... [Information of the supplier]
Gegründet 1975 unter dem Namen "Deutsche Gesellschaft für Zellbiologie e.V.". Die Zahl ihrer Mitglieder beträgt heute 1100. Das zentrale Anliegen der Zellbiologie ist die Erforschung der Lebensvorgänge und deren molekulare Regulation in der Zelle. Sowohl methodisch als auch in den experimentellen Modellen ist die Zellbiologie mehr und mehr zu einer integrativen Wissenschaft geworden. Es gibt vielfältige Überschneidungen mit Fragestellungen der Biochemie, Biophysik, Entwicklungsbiologie, Genetik, Immunologie, Mikrobiologie, Parasitologie und der medizinischen Grundlagenforschung. Auf diese Weise wurde ein umfangreiches Fachwissen von Experten vieler Fachgebiete in der Gesellschaft zusammengeführt. Die von den Zellbiologen erarbeiteten Grundlagen wirken zunehmend auf die biomedizinische Forschung ein und führten in einzelnen Fällen bereits zu einem besseren Verständnis von Krankheiten auf molekularer Ebene. Die Deutsche Gesellschaft für Zellbiologie veranstaltet eine Jahrestagung, die jedes Jahr im März in einer anderen Stadt abgehalten wird. 3mal jährlich erhält jedes Mitglied die "DGZ-Mitteilung". Die DGZ verleiht verschiedene Preise für Doktor- und Forschungsarbeiten. [vdbiol] ... [Sonstige Quelle laut Angabe]