Genes to Cognition (G2C) is a neuroscience research programme with the dual aim of discovering fundamental biological principles and important insights into brain disease. G2C is an international collaborative program initiated by Dr. Seth Grant and supported by the Wellcome Trust following the discovery that multiprotein complexes formed by intracellular proteins and neurotransmitter receptors were important for neuronal plasticity and behaviour. Multiprotein complexes are involved with dozens of brain diseases, control multiple types of behaviours and are involved with the responses to drug treatments of mental disorders. Evolutionary studies show ancient forms of the complexes evolved over a billion years in single cell animals and may represent the origin of the brain. The long term goal is to understand the molecular basis of the extraordinarily complex brain of humans, how this complexity evolved, what it confers on behaviour and why brain evolution made us susceptible to mental illness. The G2C project has a unique database called G2Cdb that houses data resources from the research program and G2C has a very interesting educational program called G2COnline. ... [Information of the supplier, modified]
The potential of a pesticide or biocide to cause adverse effects in the developing embryo or fetus is an important consideration in any health risk assessment for humans and wildlife. Such information is usually derived from experimental studies in which pregnant laboratory animals are exposed to various concentrations of compounds during critical stages of fetal development. The terms and diagnostic criteria used to describe fetal anomalies need to be consistent from one laboratory to another. Consequently, the DevTox Project has three main objectives: To harmonize the nomenclature used to describe developmental anomalies in laboratory animals, to assist in the visual recognition of developmental anomalies with the aid of photographs, and to provide a historical control database of developmental effects in laboratory animals. ... [Information of the supplier]