Proteomik ist eine sehr junge Forschungsrichtung mit einer sehr viel älteren Wurzel: der Proteinanalytik. Diese befaßt sich mit der Aufklärung von molekularen Eigenschaften wie Aminosäuresequenz, dreidimensionale Struktur und biologische Aktivität individueller Proteine. Untersuchungsgegenstand der Proteomik ist demgegenüber die Gesamtheit aller Proteine in einer biologischen Probe im Moment der Untersuchung und bei den dafür gültigen Bedingungen. Dafür wurde vor etwa 7 Jahren der Begriff "Proteom" geprägt. Die DGPF versteht sich als Plattform, um die in Deutschland an verschiedenen Standorten und im Rahmen unterschiedlicher Programme angelaufenen Proteomik-Aktivitäten unter einem Dach zusammenzuführen und darüber hinaus die Proteomforschung durch national und international abgestimmte Initiativen voranzubringen. Durch eine übergreifende Koordination soll eine Bündelung und optimale Nutzung der nationalen Forschungs-kapazitäten herbeigeführt werden, um im weltweiten Wettbewerb an führender Stelle bestehen zu können. ... [Information des Anbieters]
Ziel dieser Website ist die Bereitstellung möglichst vielfältiger Informationen über den Modellorganismus Echerichia coli K12. Diese Sammlung von Datenbanken bietet Informationen zum gesamten E.coli K12-Chromosom. Die Datenbanken können auf unterschiedliche Weise durchsucht werden: über eine Gen-/Sequenzkarte, das Scrollen durch verschiedene Tabellen oder über eine Stichwortsuche. ... [Information des Anbieters, übersetzt]
Das European Molecular Biology Laboratory ist eine Non-Profit-Organisation und ein Institut der Basisforschung, das von 18 Mitgliedsstaaten finanziert wird. Die Forschung am EMBL wird von 80 unabhängigen Gruppen, die das Spektrum der Molekularbiologie abdecken, durchgeführt. Eckpfeiler der Aufgaben des EMBL sind: Basisforschung im Bereich molekularer Biologie, Ausbildung von Wissenschaftlern, Studenten und Besuchern in allen Levels, ein grundlegender Service für Wissenschaftler der Mitgliedsstaaten, Entwicklung neuer Instrumente und Methoden in den Life Sciences und Technologietransfer. ... [Information des Anbieters, übersetzt]
Nukleotidsequenz-Datenbank des European Bioinformatics Institute (EBI), in Kooperation mit GenBank (USA) und DNA Database of Japan (DDBJ). Hier können komplette Genome und Nukleotidsequenzen gesucht werden. [Redaktion vifabio]
Individualised medicine based on patient genomes will have an enormous impact on healthcare. With breakthroughs in DNA sequencing technology, the number of sequenced genomes could reach >1 Million within 5–10 years. The simultaneous generation and integration of this associated molecular and clinical data will provide an unprecedentedly rich set of “big data” for basic research and translation. Integration of these data will provide new research opportunities, for example, through the identification of novel biomarkers or by enabling the identification of causal relationships in molecular biology through analysing complex datasets, but will also come with significant technical and bioethical challenges. This EMBL-Wellcome Genome Campus Conference on “Big Data in Biology & Health” will be held at EMBL Heidelberg, and will alternate between Heidelberg and Hinxton yearly to address the opportunities and challenges of “big data” analytics, advance basic research and explore translational opportunities. This timely interdisciplinary meeting aims to enable the European research community to participate in and help drive the future development of “big data” research, as well as raise further awareness for this new and relevant research direction in the life sciences. ... [Information of the supplier]
The principal objective of this conference series is to provide an international forum for cutting edge research in chromatin and epigenetics. This conference provides “the focal hub” for people to present their research and exchange ideas in a European venue. The organising team assembles top speakers covering the latest advances in the field, incorporating diversity in every sense (gender, geography etc). The overarching goal of this conference series is to cover chromatin regulation, chromatin dynamics, signalling to chromatin, nuclear architecture and dynamics, developmental epigenetics, epigenomics, epigenetics and human diseases, genome stability, environmental epigenetics, and transgenerational inheritance. We also include talks on latest approaches for studying these biological questions, including functional genomics, system biology and super resolution microscopy. ... [Information of the supplier]
The main objective of this conference is to bring people together from diverse disciplines to exchange ideas, promote cross-disciplinary collaborations and to form a synthesis of appropriate systems-level approaches. The meeting is therefore purposely broad to cover all aspects of genomics to systems biology, a unique combination that is highly appreciated by the participants. Over the past decade, this EMBO conference has therefore served as an important venue in helping to shape the field, or to be more precise to help generate a community of scientists that come from very diverse disciplines, each with the common goal to understand the systems level properties of their system of interest. Topics: Transcription, chromatin and nucleosomes; 3D structure, epigenetics; Post-transcriptional regulation and non-coding RNA; Proteomics, protein-protein interaction networks, metabolites; Genetic interaction networks; Single cell variation, biological noise; Systems Genetics, genotype to phenotype; Human genome variation; Data integration, Modelling and prediction. ... [Information of the supplier]
Several RNA viruses constitute the majority of emerging and re-emerging pathogens, however, there is very little focus on research into the biology and pathogenesis of RNA viruses in India. Studies on epidemiology and disease burden, risk factors, the immune response to RNA viruses, circulating virus strains and virus evolution, animal models of disease, antivirals and vaccines are strikingly absent. Emerging RNA viruses such as Zika virus and Crimean-Congo haemorrhagic fever virus are a matter of grave concern to India. Therefore, this symposium will play a key role in bringing together national and international RNA virus experts from diverse areas on one platform to guide the future of RNA virus research in India. This symposium will provide impetus on laying a strong foundation for both the fundamental and translational aspects of RNA virus biology with a focus on epidemiology, immune response, virus evolution and vaccine trials. ... [Information of the supplier]
Big data analytics is transforming biology and medicine by allowing researchers to extract more information and knowledge from rapidly growing diverse types of data. This India-EMBO Symposium focuses on the translational interface of big data with biomedicine at various scales ranging from microbes to societies. The meeting, other than summarizing the potential of such applications and practical challenges therein, will specifically discuss the different requirements and the need for calibrating big data analytics to the larger purpose of the "actionable information." A computational model for prioritizing drug candidates that will undergo further pre-clinical and clinical testing, vastly differs in terms of error tolerance, from the use of large datasets to form public health policy evidence. Specifically, the "actionability" of any insight would be guided by pragmatic concerns and ethics, which vary between applications. Thus, the emphasis will be to form a well reasoned articulation ... [Information of the supplier]
There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Several human diseases, including cancer, have already been linked to DNA replication stress, a term that refers to perturbations in DNA replication. Therefore, a better understanding of how cells respond to this will help us understand disease development and responses to therapy. By bringing together experts in the basic biology of DNA replication and DNA replication stress, this symposium aims to fuel further progress in these important fields. ... [Information of the supplier]