In the year 2003 scientists from around Germany initiated the establishment of the German Society for Stem Cell Research (GSZ) with emphasis on basic research in stem cell biology. The society is a non-profit organisation, financially and politically autonomous, and is registered with the district court Cologne under the number VR 14639 since November 4th 2004. The main purpose of the society is to promote stem cell research. In order to achieve this goal the society will promote the stem cell research in basic research and in academic teaching by allocating available funds to support training programs, to organize seminars and conferences, as well as instigating the exchange of students and scientists on national and international level for collaborative projects and resulting publications. ... [Information of the supplier]
Most organisms have a defined lifespan, however life of a species continues and evolves via germline from generation to generation. Recent studies show that tissue stem cells share molecular and developmental signatures with the germline and that even fully differentiated, postmitotic cells can be reprogrammed to regain totipotency. This EMBO/EMBL Symposium will go beyond a description of the phenomena involving stem cell behaviour, programming and reprogramming. It will bring together researchers from different disciplines, who will address fundamental questions of totipotency as they relate to evolution, development and tissue specialization. ... [Information of the supplier]
The International Society of Developmental Biologists (ISDB) is a non-profit scientific association which has as its aim the promotion of the study of developmental biology. To this effect, the ISDB also organises and supports scientific meetings and workshops. Formerly known as the International Institute of Embryology (IIE), the ISDB was renamed in September 1968. The International Society of Developmental Biologists consists of individual members and society members. ... [Information of the supplier]
The internet Primate Aging Database (iPAD) is a multi-centered, relational database of biological variables in aging, captive nonhuman primates. Through joint initiative of the National Institute on Aging (intramural and extramural programs), National Center for Research Resources (NCRR), and the National Primate Research Center at the University of Wisconsin-Madison (WNPRC), we have organized a database to study biomarkers of aging in nonhuman primates. iPAD also provides an invaluable veterinary and clinical resource, and can generate normative data for numbers of animals across research settings. iPAD now contains over 400,000 data points for body weight, blood chemistry and hematology, for healthy, non-experimental subjects across time. ... [Information of the supplier]
LarvalBase is a comprehensive information system on fish larvae that are relevant in the field of fisheries research and finfish aquaculture, combining traditional sources such as primary and “grey” literature. In addition, data from various sources as Internet and e.g. from practising aquaculturists, even in developing countries, are considered to be valuable for the database. (...) The LarvalBase-Project was started in the beginning of 1998 in close conjunction with FishBase, the largest data base on finfish worldwide (FishBase). However, FishBase holds little information on ichthyoplankton and lacks detailled data on fish larvae identification and rearing. The LarvalBase-Project aimed close these gaps. ... [Information of the supplier, modified]
EMAGE is a database of in situ gene expression data in the mouse embryo and an accompanying suite of tools to search and analyse the data. mRNA in situ hybridisation, protein immunohistochemistry and transgenic reporter data is included. These are sourced from the community and our curators take this data and describe it in a standardised way that allows data query and exchange. The description includes a text-based component but the unique aspect of EMAGE is its spatial annotation focus. It is the mission at EMAGE: a) To provide a focal point for biomedical and clinical researchers to access mouse embryo in situ gene expression data sourced from the community, b) To offer high-quality curation and annotation of this data in the spatio-temporal and anatomical framework of the EMAP Digital Atlas, c) To generate and offer methods for analysis of this data and d)To provide EMAGE in the broader context of other bioinformatics resources to generate a tool for understanding the genetic control of mouse development. ... [Information of the supplier]
The newt Notopthalmus viridescens is the master of regeneration. This organism is known for more than 200 years for its exceptional regenerative capabilities. Newts can completely replace lost appendages like limb and tail, lens and retina and parts of the central nervous system. Moreover, after cardiac injury newts can rebuild the functional myocardium with no scar formation. To date only very limited information from public databases is available. Newt-Omics aims to provide a comprehensive platform of expressed genes during tissue regeneration, including extensive annotations, expression data and experimentally verified peptide sequences with yet no homology to other publically available gene sequences. The goal is to obtain a detailed understanding of the molecular processes underlying tissue regeneration in the newt,that may lead to the development of approaches, efficiently stimulating regenerative pathways in mammalians. ... [Information of the supplier]
Driven by a need to improve our understanding of molecular processes that are common and unique across cancer stem cells (CSCs), we have developed the Stem Cell Discovery Engine (SCDE)—an online database of curated CSC experiments coupled to the Galaxy analytical framework. The SCDE allows users to consistently describe, share and compare CSC data at the gene and pathway level. Our initial focus has been on carefully curating tissue and cancer stem cell-related experiments from blood, intestine and brain to create a high quality resource containing 53 public studies and 1098 assays. The experimental information is captured and stored in the multi-omics Investigation/Study/Assay (ISA-Tab) format and can be queried in the data repository. (Taken from: Shannan J. Ho Sui, Kimberly Begley, Dorothy Reilly, Brad Chapman, Ray McGovern, Philippe Rocca-Sera, Eamonn Maguire, Gabriel M. Altschuler, Terah A. A. Hansen, Ramakrishna Sompallae, Andrei Krivtsov, Ramesh A. Shivdasani, Scott A. Armstrong, Aedín C. Culhane, Mick Correll, Susanna-Assunta Sansone, Oliver Hofmann, and Winston Hide: The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons. In: Nucl. Acids Res. (2012) 40(D1): D984-D991) ... [Miscellaneous as indicated]
Planarians are free-living (non-parasitic) freshwater organisms possessing derivatives of all three germ layers (i.e., ectoderm, mesoderm and endoderm). These animals are renowned for their developmental plasticity and have attracted the attention of generations of biologists (http://planaria.neuro.utah.edu). Among all flatworm species studied thus far, the planarian Schmidtea mediterranea is rapidly emerging as a key model organism for the study of regeneration, tissue homeostasis and stem cell biology. The Schmidtea mediterranea Genome Database (SmedGD) is a GMOD compliant database that integrates in a single web-accessible portal all available data associated with the planarian genome, including predicted and annotated genes, ESTs, protein homologies, gene expression patterns and RNAi phenotypes. ... [Information of the supplier]
The Interactive Fly - a cyberspace guide to Drosophila development and metazoan evolution - was first released July/August 1996, with updates provided at approximately one month intervals, through September 1997 (edition 13). Updating quarterly started with edition 14. With edition 40, the Interactive Fly began to schedule updates three times a year: fall, winter and spring. ... [Information of the supplier, modified]