Detailed overview:
BSRD: Bacterial Small Regulatory RNA Database
BSRD: Bacterial Small Regulatory RNA Database
| Title: | BSRD: Bacterial Small Regulatory RNA Database |
| Title abbreviated: | BSRD |
| Identifier: | http://kwanlab.bio.cuhk.edu.hk/BSRD/ |
| Creator: | Li, Lei; et al. |
| Abstract: | In bacteria, small (~30-500 nt) non-coding RNAs (sRNAs) are the most abundant class of post-transcriptional regulators that are involved in diverse processes including quorum sensing, stress response, virulence and carbon metabolism. Based on the target molecules, sRNAs can be divided into two major groups: (i) mRNA-binding antisense sRNAs and (ii) protein-binding sRNAs. The antisense RNAs can further be categorized as cis-encoded antisense sRNAs, which are completely complementary to their targets, and trans-encoded antisense sRNAs, which are only partially complementary to their targets. In any case, the interaction between antisense RNAs and target mRNAs could direct a plethora of biological regulatory circuits. Recent developments in high-throughput techniques, such as genomic tiling arrays and RNA-Seq have provided invaluable insights into the detection and characterization of bacterial sRNAs. However, a comprehensive bacterial sRNA database is not yet available, especially for integrating and analyzing high-throughput sequencing data. Here, we have designed and constructed BSRD (Bacterial Small regulatory RNA Database) which hosts sRNAs collected from over 783 bacterial species and 957 strains. [Information of the supplier] |
| Subject: |
Metabolism in biochemical genetics (572.84); RNA (Ribonucleic acid) (572.88) » find similar sources! |
| Audience: | Experts |
| Language: | English |
| Format: | database |
| Resource type: | Factual databases |
| Access: | free |
| Metadata update date: | 2013-11-29 |
| Metadata provider: |
 |
| URL of this vifabio-resource: | http://www.vifabio.de/en/iqfBio/detail/8280 |
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