|Title:||CREB Target Gene Database|
|Abstract:||The cyclic AMP response element (CRE)-binding protein (CREB) family of activators (CREB1, CREM, ATF1) functions in diverse physiological processes, including the control of cellular metabolism, growth-factor-dependent cell survival, and developement an plasticity of neurons. A diverse range of signals, including cAMP, calcium, stress and mitogenic stimuli, can activate CREB and promote target gene expression. This database is dedicated to catogerize CREB target genes in a comprehensive and easy-to-search way. We have used a multi-layered approach to predict, validate and chracterize CREB target genes. For each gene, we try to provide the following information: 1. CREB binding sites on the promoters, 2. Promoter occupancy by CREB, 3. Gene activation by cAMP in tissues. The data are for humans, rats, and mice. [Information of the supplier, modified]|
Biochemical genetics in animals (572.81)
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|Resource type:||Factual databases|
|Metadata update date:||2015-09-10|
|URL of this vifabio-resource:||http://www.vifabio.de/en/iqfBio/detail/1495|
|© Virtuelle Fachbibliothek Biologie (vifabio)|