PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes. Each entry in PHI-base is curated by domain experts and is supported by strong experimental evidence (gene disruption experiments, STM etc), as well as literature references in which the original experiments are described. Each gene in PHI-base is presented with its nucleotide and deduced amino acid sequence, as well as a detailed description of the predicted protein's function during the host infection process. To facilitate data interoperability, we have annotated genes using controlled vocabularies and links to external sources. ... [Information of the supplier]
The purpose is the creation of a comprehensive computer supported decision/help system for pharmacotherapy and clinical toxicology. At present, CliniPharm/CliniTox has the following components: 1) an animal medicine compendium for Switzerland; 2) specialist information about therapeutic substances; 3) CliniTox, a computer supported decision/help system for the management of cases of poisoning in animals (incl. a poisonous plant database that contains, besides relevant veterinary medical data, botanical information as well as pictures of the individual plants. Because of the multilingual nature of Switzerland the plants can be searched for not only by their scientific names, but also by their common German, French, Italian, and English names.) ... [Information of the supplier, translated and modified]
The Ecological Database of the World's Insect Pathogens (EDWIP) offers information on fungi, viruses, protozoa, mollicutes, nematodes, and bacteria¹ that are infectious in insects, mites, and related arthropods. Data in EDWIP include associations (or lack thereof) between pathogenic organisms and insect, mite, and other arthropod hosts. EDWIP also includes information on where associations have been observed, stages and tissues of hosts infected, and habitats and host ranges of the arthropod hosts. Association and nonassociation data in EDWIP are supported by bibliographic citations. All areas of the database are searchable. (....) ¹Because of the tremendous volume of information available on the bacterial pathogen Bacillus thuringiensis, we have excluded this species from EDWIP. For informaton on Bt, see the Canadian Forest Service's Bt Toxin Specificity Database. ... [Information of the supplier]
The ECOTOXicology database (ECOTOX) is a source for locating single chemical toxicity data for aquatic life, terrestrial plants and wildlife. ECOTOX was created and is maintained by the U.S.EPA, Office of Research and Development (ORD) , and the National Health and Environmental Effects Research Laboratory's (NHEERL's) Mid-Continent Ecology Division (MED). ECOTOX integrates three previously independent databases - AQUIRE, PHYTOTOX, and TERRETOX - into a unique system which includes toxicity data derived predominately from the peer-reviewed literature, for aquatic life, terrestrial plants, and terrestrial wildlife, respectively. ... [Information of the supplier]
IMGT is a high-quality integrated knowledge resource specialized in the immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC), immunoglobulin superfamily and related proteins of the immune system (RPI) of human and other vertebrate species. IMGT consists of sequence databases (IMGT/LIGM-DB, a comprehensive database of IG and TR from human and other vertebrates, with translation for fully annotated sequences, IMGT/MHC-DB, IMGT/PRIMER-DB), genome database (IMGT/GENE-DB) and structure database (IMGT/3Dstructure-DB), Web resources (IMGT Marie-Paule page) and interactive tools. The IMGT Home page http://imgt.cines.fr (Montpellier, France) provides a common access to all Immunogenetics data. ... [Information of the supplier]
TOXLINE consists of two components: TOXLINE Special and TOXLINE Core. TOXLINE Special is a TOXNET component created by merging all or selected records from several databases, some of which are archival (i.e., no longer being updated). The databases or portions thereof that are included are referred to as TOXLINE Special subfiles. The active collection consists of subfiles that are periodically updated. Most of TOXLINE's records contain abstracts, although some do not. Most of the above subfiles are indexed using keywords, although the vocabularies differ. You may search using specific controlled vocabulary terms for a subfile, if you are familiar with them. However, any terms you enter in the query box will automatically be searched against both the keyword and MeSH fields, in addition to other fields such as title, abstract, and author. TOXLINE Core is a MEDLINE subset of journal literature limited to toxicology and environmental health, and searchable via NLM's PubMed interface. TOXLINE Core is roughly equivalent to the former TOXBIB subfile of TOXLINE, which was also a MEDLINE subset. ... [Information of the supplier, modified]
The Cornell Plant Pathology Herbarium (CUP) is a large research collection of preserved fungi and other organisms that cause plant diseases. CUP is the fourth or fifth largest mycological herbarium in North America. We hold about 400,000 fungus and plant disease specimens, including over 7000 type specimens, each the first of its kind to be described and named. The CUP Photograph Collection includes about 60,000 historical scientific photographs of mushrooms, agricultural practices, plant diseases, and portraits. ... [Information of the supplier]
The Cornell Plant Pathology Herbarium (CUP) is home to several major photograph collections, together amounting to over 60,000 prints and negatives. A small fraction of our photos have been digitized and can be viewed through this site. Our collections document the last 120 years of plant pathology, mycology, and agricultural practice. Many photographs are tied to specimens in our specimen collection, making them uniquely useful for biological research. ... [Information of the supplier]
HSDB is a toxicology data file on the National Library of Medicine's (NLM) Toxicology Data Network (TOXNET®). It focuses on the toxicology of potentially hazardous chemicals. It is enhanced with information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data are referenced and derived from a core set of books, government documents, technical reports and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review Panel (SRP), a committee of experts in the major subject areas within the data bank's scope. HSDB is organized into individual chemical records, and contains over 5000 such records. ... [Information of the supplier]
Antimicrobial peptides, also referred to as host defense peptides or "alarmins", have been identified in nearly all life forms, ranging from bacteria, fungi, plants, insects, amphibians, to mammals, including humans. As the key component of the innate immunity, these ancient peptides effectively eliminate invanding microbes such as bacteria, viruses, fungi, and parasites. It is commonly believed that cationic antimicrobial peptides exert their effects via attacking anionic bacterial membranes. Currently, there is high interest worldwide in this topic with a goal of understanding the mechanism of action and developing natural antimicrobial peptides into a new generation of antibiotics. To promote the research, education, and information exchange in the field, we have created this antimicrobial peptide database and data analysis system. The data stored in APD2 were gleaned from the Protein Data Bank (PDB), Swiss-Prot Protein Knowledgebase and PubMed National Library of Medicine. The peptides in this database are in the mature and active form and primarily from natural sources ranging from bacteria, plants, insects, to animals. ... [Information of the supplier]