Driven by a need to improve our understanding of molecular processes that are common and unique across cancer stem cells (CSCs), we have developed the Stem Cell Discovery Engine (SCDE)—an online database of curated CSC experiments coupled to the Galaxy analytical framework. The SCDE allows users to consistently describe, share and compare CSC data at the gene and pathway level. Our initial focus has been on carefully curating tissue and cancer stem cell-related experiments from blood, intestine and brain to create a high quality resource containing 53 public studies and 1098 assays. The experimental information is captured and stored in the multi-omics Investigation/Study/Assay (ISA-Tab) format and can be queried in the data repository. (Taken from: Shannan J. Ho Sui, Kimberly Begley, Dorothy Reilly, Brad Chapman, Ray McGovern, Philippe Rocca-Sera, Eamonn Maguire, Gabriel M. Altschuler, Terah A. A. Hansen, Ramakrishna Sompallae, Andrei Krivtsov, Ramesh A. Shivdasani, Scott A. Armstrong, Aedín C. Culhane, Mick Correll, Susanna-Assunta Sansone, Oliver Hofmann, and Winston Hide: The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons. In: Nucl. Acids Res. (2012) 40(D1): D984-D991) ... [Miscellaneous as indicated]
Planarians are free-living (non-parasitic) freshwater organisms possessing derivatives of all three germ layers (i.e., ectoderm, mesoderm and endoderm). These animals are renowned for their developmental plasticity and have attracted the attention of generations of biologists (http://planaria.neuro.utah.edu). Among all flatworm species studied thus far, the planarian Schmidtea mediterranea is rapidly emerging as a key model organism for the study of regeneration, tissue homeostasis and stem cell biology. The Schmidtea mediterranea Genome Database (SmedGD) is a GMOD compliant database that integrates in a single web-accessible portal all available data associated with the planarian genome, including predicted and annotated genes, ESTs, protein homologies, gene expression patterns and RNAi phenotypes. ... [Information of the supplier]
The International Zebrafish Protein Trap Consortium welcomes you to our database. We currently have teams in the United States, Germany, India, Canada, and Singapore implementing gene-break transposons to create expression-tagged, revertible mutations in zebrafish genes. We provide database services on zfishbook for GBT mutagenesis projects in zebrafish regardless of scale to promote shared use of these valuable resources. (...) zfishbook is a real-time database with full and unrestricted access to all information. Registration allows you to save your favorite lines for easy access, request lines from the Mayo Clinic catalog, contribute to line annotation with appropriate credit, and puts you on an optional mailing list for future zfishbook newletters and updates. We welcome participation from any and all of our peer zebrafish colleagues. Therefore please consider registering to help annotate your favorite tissues and expression domains. ... [Information of the supplier, modified]
